نتایج جستجو برای: betaine homocysteine methyltransferase bhmt

تعداد نتایج: 34463  

2016
Dragan Hrnčić Nikola Šutulović Aleksandra Rašić-Marković Bojana Rankov-Petrović Dragan Djurić Olivera Stanojlović

OBJECTIVES: The aim of this study was to determine the effects of acute, single boost of physical activity on seizures induced by homocysteine thiolactone in rats, using treadmill for small experimental animals as a paradigm of physical activity. MATERIAL AND METHODS: After adaptation to the treadmill, Wistar albino rats were randomly divided into acute physical activity and sedentary group. An...

2012
Michael Lever Sandy Slow David O McGregor Warwick J Dellow Peter M George Stephen T Chambers

BACKGROUND Since betaine is an osmolyte and methyl donor, and abnormal betaine loss is common in diabetes mellitus (>20% patients), we investigated the relationship between betaine and the post-methionine load rise in homocysteine, in diabetes and control subjects. The post-methionine load test is reported to be both an independent vascular risk factor and a measure of betaine sufficiency. ME...

2002
Ursula Schwab Anneli Törrönen Leena Toppinen Georg Alfthan Markku Saarinen Antti Aro Matti Uusitupa

Background: Betaine (trimethylglycine) is found in several tissues in humans. It is involved in homocysteine metabolism as an alternative methyl donor and is used in the treatment of homocystinuria in humans. In pigs, betaine decreases the amount of adipose tissue. Objective: The aim of the study was to examine the effect of betaine supplementation on body weight, body composition, plasma homoc...

Journal: :Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2003

2014
Hui Zhang Qi Sun Teng Liu Lu Ma Panpan Zhen Ke Wang Lingqiao Lu Xin Liu Xin Zhang Dandan Song Xiaoyun Zuo Huirong Liu Wen Wang

Hyperhomocysteinemia is strongly associated with cardiovascular diseases. Previous studies have shown that phytoestrogen α-zearalanol can protect cardiovascular system from hyperhomocysteinemia and ameliorate the level of plasma total homocysteine; however, the underlying mechanisms remain to be clarified. The aim of this research is to investigate the possible molecular mechanisms involved in ...

Journal: :Iranian journal of kidney diseases 2009
Shahrzad Ossareh Hossein Shayan-Moghaddam Ashraf Salimi Mojgan Asgari Farhat Farrokhi

INTRODUCTION We compared the effect of higher and lower doses of folic acid compared to our routine daily dose on plasma homocysteine levels, in our hemodialysis patients. MATERIALS AND METHODS Eighty patients on hemodialysis receiving oral folic acid, 10 mg/d, were randomized to receive folic acid at either doses of 5 mg/d (group 1) or 15 mg/d (group 2) for 2 months. Plasma levels of total h...

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