In human PMN (polymorphonuclear cells), challenged by P-selectin, the beta2-integrin Mac-1 (macrophage antigen-1) promoted the activation of the SRC (cellular homologue of Rous sarcoma virus oncogenic protein) family members HCK (haematopoietic cell kinase) and LYN (an SRC family protein tyrosine kinase) and phosphorylation of a P-110 (110 kDa protein). SRC kinase activity in turn was necessary...

Objectives: Destructive spondyloarthropathy (dSpA) occurs due to inflammatory destruction of axial joints beta2-microglobulin (beta2-M) accumulation in patients with end-stage renal disease (ESRD) receiving replacement therapy (RRT). This study aimed investigate the frequency dSpA ESRD RRT, by diagnostic criteria sets back pain (IBP) and classical SpA.
 Methods: A total 140 were included. ...

In this article we will review the role of long acting beta2-adrenoreceptor agonists and long-acting muscarinic agents in the management of airflow obstruction. We will then focus our attention on indacaterol, one of the new once daily inhaled beta2-adrenoreceptor agonists. Pharmacologically this drug is a nearly full beta2-agonist without loss of efficacy after prolonged administration. We wil...

BACKGROUND The metabolic syndrome (MetS) is a proatherogenic entity. Autoantibodies to phospholipid cofactors such as beta2-glycoprotein I (beta2-gpI) can influence atheroma appearance. Previous studies confirmed an association of IgA anti-beta2-gpI antibodies with cerebral ischemia, myocardial infarction, peripheral artery disease and carotid disease. OBJECTIVE This case-control study evalua...

OBJECTIVES To clarify the causes of death of residents with renal tubular dysfunction induced by cadmium (Cd) in the environment. METHODS A 15 year follow up study was performed with the inhabitants living in the Cd polluted Kakehashi River basin in Japan. Standardised mortality ratios (SMRs) for causes of death, classified by ICD-9, were computed using the person-years method to investigate ...

Different beta 1 and 2 adrenergic receptors agonists might have various biological and physiological effects on fish species. An experiment was designed to study the effects of feeding ractopamine, terbutaline and metaproterenol; as beta1, beta2 and less selective beta2 adrenergic receptor agonists, respectively; on body weight gain, feed conversion rate, concentration of biochemical parameters...

Introduction: Paranormal beliefs are defined as believing in extrasensory perception, precognition, witchcraft, and telekinesis, magical thinking, psychokinesis, superstitions. Previous studies corroborate that executive brain functions underpin paranormal beliefs. To test causal hypotheses, neurophysiological studies of brain activity are required. Method: A sample of 20 students (10 females,...