Photosensitivity is a characteristic feature of some inflammatory skin diseases, including cutaneous lupus erythematosus (CLE) and dermatomyositis (DM). Among the various hypotheses that explain this phenomenon, an aberrant sensitivity keratinocytes (KC) deserves more attention, especially in case UVB photosensitivity, as epidermis almost entirely absorbs UVB. However, underlying mechanisms UVB...

We investigated the effects of ultraviolet A1 (UVA1) irradiation on spontaneous lupus erythematosus- (LE-) like skin lesions of MRL/lpr mice, using a disease prevention model. UVA1 irradiation significantly inhibited the development of LE-like skin lesions, without obvious changes of the disease including renal disease and serum antinuclear antibody levels. Besides the massive infiltration of m...

OBJECTIVE The purpose of this study was to investigate the rat skin penetration abilities of two commercially available low-level laser therapy (LLLT) devices during 150 sec of irradiation. BACKGROUND DATA Effective LLLT irradiation typically lasts from 20 sec up to a few minutes, but the LLLT time-profiles for skin penetration of light energy have not yet been investigated. MATERIALS AND M...

The skin anti-aging effects of orally administered salmon nasal cartilage extract (SNCE), which includes abundant proteoglycan, were investigated using a hairless mouse skin-aging model, in which aging was caused by repetitive ultraviolet B (UV-B) irradiation. Physiological analysis of the skin surface following repetitive UV-B irradiation of 8 weeks revealed inhibition of erythema levels and r...

The performances of Low Gain Avalanche Diode (LGAD) sensors from a neutron irradiation campaign with fluences 0.8 × 1015, 1.5 1015 and 2.5 neq/cm2 are reported in this article. These LGAD developed by the Institute High Energy Physics, Chinese Academy Sciences Novel Device Laboratory for Granularity Timing Detector Luminosity Large Hadron Collider. timing resolution collected charge were measur...

Non-melanoma skin cancer (NMSC) is the most common type of cancer. Increased expression and activity of Rac1, a small Rho GTPase, has been shown previously in NMSC and other human cancers; suggesting that Rac1 may function as an oncogene in skin. DMBA/TPA skin carcinogenesis studies in mice have shown that Rac1 is required for chemically induced skin papilloma formation. However, UVB radiation ...

BACKGROUND The outcome of glaucoma surgery can be affected by the rate at which the surgical wound heals. Beta radiation has been proposed as a rapid and simple treatment to slow down the healing response. OBJECTIVES To assess the effectiveness of beta radiation during glaucoma surgery (trabeculectomy). SEARCH STRATEGY We searched the Cochrane Central Register of Controlled Trials (CENTRAL)...

Epidermal filaggrin level is affected by ultraviolet B irradiation in animal and experimental models. This study examined the effect of ultraviolet B irradiation on epidermal filaggrin and natural moisturizing factors in vivo in healthy adults (n = 22). Participants were irradiated with 2 minimal erythema doses of ultraviolet B on the skin. Biopsies and tape strips were collected from skin irra...