The r.m.s. deviation from the mean plane for the non-H atoms in the title compound, C(7)H(5)BrN(2)S, is 0.011 Å. In the crystal, the mol-ecules are linked by N-H⋯N and N-H⋯Br hydrogen bonds to generate (010) sheets. Weak aromatic π-π stacking [centroid-to-centroid separation = 3.884 (10) Å] and possible C-H⋯Br inter-actions are also observed. The crystal studied was found to be an inversion twin.

In the title compound, C(12)H(11)ClN(2), the dihedral angle between the benzene and pyridyl rings is 48.03 (8)°. Twists are also evident in the mol-ecule, in particular about the N(a)-C(b) (a = amine and b = benzene) bond [C-N-C-C = -144.79 (18)°]. In the crystal, inversion dimers linked by pairs of N-H⋯N hydrogen bonds result in the formation of eight-membered {⋯NCNH}(2) synthons [or R(2) (2)(...

Two independent mol-ecules comprise the asymmetric unit in the title compound, C(11)H(11)N(3). These differ in terms of the relative orientations of the aromatic rings: the first is somewhat twisted, while the second is approximately planar [dihedral angles between the pyrimidine and phenyl rings = 39.00 (8) and 4.59 (11)°]. The mol-ecules also form distinct patterns in their hydrogen bonding. ...

The title compound, C(14)H(11)N(3)OS, was synthesized by the reaction of phenoxy-benzoic acid and thio-semicarbazide. The thia-diazole ring makes dihedral angles of 0.99 (16) and 86.53 (18)°, respectively, with the benzene and phenyl rings. The dihedral angle between the benzene and phenyl rings is 87.17 (19)°. Intra-molecular C-H⋯S contacts are present. In the crystal, inter-molecular N-H⋯N hy...

The Hg atom in the title compound, [HgCl(2)(C(13)H(14)N(2))], adopts a distorted tetra-hedral geometry, being ligated by two N atoms of the benzyl(2-pyridylmeth-yl)amine (bpma) ligand and two Cl atoms. The dihedral angle between the least-squares planes through the chelate ring and Cl-Hg-Cl atoms is 85.4 (1)°. The phenyl ring on the bpma ligand is twisted out of the pyridine plane, forming a di...

In the title compound, C(12)H(14)N(2)S, the dihedral angle between the 1,3,5-trimethyl-benzene and 1,3-thia-zol-2-amine groups is 73.15 (4)°. In the crystal, inversion dimers linked by pairs of N-H⋯N hydrogen bonds generate R(2) (2)(8) loops.

In the crystal structure of the title compound, C(9)H(9)N(3)O, adjacent mol-ecules are linked through N-H⋯N hydrogen bonds into a three-dimensional network.

The title compound, C(11)H(11)N(3), was synthesized as part of our research into functionalized pyrimidines. It crystallizes with two independent mol-ecules in the asymmetric unit that differ only in the twist between the two aromatic rings; the torsion angles between the rings are 29.9 (2) and 45.1 (2)°. The crystal packing is dominated by inter-molecular N-H⋯N hydrogen bonds between independe...

The asymmetric unit of the title compound, C15H12ClN3, contains two independent mol-ecules. The quinazoline ring system in each is essentially planar, with maximum deviations of 0.025 (16) and 0.0171 (16) Å. The dihedral angles between quinazoline ring systems and the phenyl rings are 88.25 (8) and 85.28 (16)° in the two independent mol-ecules. In the crystal, alternating independent mol-ecules...

Small optically active molecules, and more particularly short-chain chiral amines, are key compounds in the chemical industry precursors of various pharmaceuticals. Their chemo-biocatalytic production on a commercial scale is already established, mainly through lipase-catalyzed resolutions leading to ChiPros™ products among others. Nevertheless, their biocatalytic synthesis remains challenging ...