The crystal structure of the title compound, [Re6Se8{NCC(CH3)3}(Et3P)5](SbF6)2·NCC(CH3)3, contains a face-capped octa-hedral [Re6(μ3-Se)8](2+) cluster core. The pseudo-centrosymmetric [Re6Se8](2+) cluster core is bonded through the Re atoms to five tri-ethyl-phosphane ligands and one tri-methyl-aceto-nitrile ligand. No significant interactions are observed between the cationic cluster, the SbF6...

In the title compound, C28H23N3O, the 1,2,4-triazole ring deviates slightly from planarity adopting a (N3)TC2 conformation which is distorted towards an EC2 conformation. The plane around the ethyl-ene unit makes a dihedral angle of 17.32 (11)° with the mean plane [r.m.s. deviation = 0.036 (1) Å] of the 1,2,4-triazole fragment. The dihedral angles between the four phenyl rings and the 1,2,4-tri...

Among the various exogenous agents inducing developmental anomalies in higher mammals, administration of chemicals to pregnant animals may be a suitable means for the detection of the mechanism of teratogenesis. Sinclair ('50) recognized an abnormality of the nervous system of embryos after treatment of pregnant mice of an albino stock for several days from 7-8th day of gestation, with ethyl-ur...

The crystal structure of the title compound, C(17)H(15)BrO(3), a chalcone derivative, exhibits two crystallographically independent mol-ecules per asymmetric unit showing an E conformation about the ethyl-ene double bond. In each mol-ecule, the two phenyl rings are almost coplanar: the mean planes make dihedral angles of 9.3 (2) and 19.4 (2)°. In the crystal, mol-ecules are linked through weak ...

In the title compound, [Pd(C(8)H(10)N)(C(2)H(8)N(2))](C(9)H(9)O(2)), the palladium ion is coordinated in a distorted square-planar fashion by the two N atoms from the chelating ethyl-enediamine group and by the N and a C atom of the deprotonated chiral amine. The resulting cationic complex and the 3,5-dimethyl-benzoate anion are inter-connected by N-H⋯O hydrogen bonds.

In the title compound, C24H20N6O, the pyridin-3-yl groups on the ethyl-ene fragment are found in a trans conformation with a C(py)-C(e)-C(e)-C(py) (py = pyridine, e = ethylene) torsion angle of 179.2 (3)°. The dihedral angle between the pyridine rings is 3.5 (1)°. In the crystal, N-H⋯N and C-H⋯O=C inter-actions form a layer arrangement parallel to the bc plane. The compound displays disorder of...

Two independent mol-ecules comprise the asymmetric unit of the title compound, C(20)H(16)ClNO, which differ in the orientation of the chalcone residue with respect to the quinoline ring [the C-C-C(=O)-C torsion angles are 69.5 (2) and 86.0 (2)°]. The configuration about each of the ethyl-ene bonds [1.342 (2) and 1.338 (2) Å] is E. The three-dimensional crystal structure is stabilized by a combi...

We describe an isotope coding strategy that enables simultaneous GC-MS analysis of multiple samples for substrate identification and quantification. The method relies on direct measurement of isotopic ethyl carbenium ions serving as mass spectral tags in a zone of minimal interference (ZMI) at m/z 31-37. Sample aldehyde and ketone mixtures were reacted with isotopic 2-aminooxyethyl propionates ...

We studied the local anesthetic effects of the quaternary lidocaine analogues QX-314, QX-572, and QX-222, the tertiary amine lidocaine, its analogues tocainide, 6603, 6211, and the neutral local anesthetic benzocaine to determine if molecular charge of antiarrhythmic agents influences their local anesthetic effects on heart fibers. We used standard microelectrode techniques and canine cardiac P...