BEL is a probabilistic description logic (DL) that extends the light-weight DL EL with a joint probability distribution over the axioms, expressed with the help of a Bayesian network (BN). In recent work it has been shown that the complexity of standard logical reasoning in BEL is the same as performing probabilistic inferences over the BN. In this paper we consider conjunctive query answering ...

The docosahexaenoic (DHA), a ω-3 fatty acid, could play a beneficial inhibition of the incidence and progress of a series of human diseases including cancer. It has been report that DHA is involved in cell apoptosis. Recent studies show that the signal transduction pathway links with bcl-2, bax, caspase-3 and MMP-9 molecules. Therefore, we tested the relationship between DHA and cell apoptosis ...

Summary Biological Expression Language (BEL) assembles knowledge networks from biological relations across multiple modes and scales. Here, we present PyBEL; a software package for parsing, validating, converting, storing, querying, and visualizing networks encoded in BEL. Availability and implementation PyBEL is implemented in platform-independent, universal Python code. Its source is distri...

We introduce the new probabilistic description logic (DL) BEL, which extends the light-weight DL EL with the possibility of expressing uncertainty about the validity of some knowledge. Contrary to other probabilistic DLs, BEL is designed to represent classical knowledge that depends on an uncertain context; that is, some of the knowledge may hold or not depending on the current situation. The p...

Point-based algorithms and RTDP-Bel are approximate methods for solving POMDPs that replace the full updates of parallel value iteration by faster and more effective updates at selected beliefs. An important difference between the two methods is that the former adopt Sondik’s representation of the value function, while the latter uses a tabular representation and a discretization function. The ...

Metformin plays an anti-proliferative role in tumor cells in many types of cancer. However, the correlation between metformin and sensitivity to chemotherapeutic agents in hepatocellular carcinoma (HCC) and the relevant mechanism are unclear. The present study showed that HCC patients with type 2 diabetes mellitus benefited from metformin administration, with a longer overall survival. Metformi...

The Bayesian Description Logic (BDL) BEL is a probabilistic DL, which extends the lightweight DL EL by defining a joint probability distribution over EL axioms with the help of a Bayesian network (BN). In the recent work, extensions of standard logical reasoning tasks in BEL are shown to be reducible to inferences in BNs. This work concentrates on a more general reasoning task, namely on conjun...

Marcanine A was isolated from the stems of Polyalthia plagioneura as light yellow crystals. The molecular and crystal structures have been determined by 1D,2D-NMR and X-ray diffraction analysis. It crystallizes in the triclinic system, space group P-1 with a = 5.2140(5)Å, b = 10.1871(11)Å, c = 11.0709(13)Å, α = 110.452(2)º, β = 103.376(2)°, γ = 90.1870(10)°, V = 533.74(10)A3, Z = 2. There are t...