Cordycepin (3′-deoxyadenosine) exhibits antimicrobial, anticancer, antimetastatic, immunomodulatory and insecticidal effects, and is one of the most important bioactive anticancer agents found in Cordyceps species (summer grass-winter worm). However, due to the requirements of specific hosts and strict growth environments, Cordyceps militaris is very scarce in nature. Therefore, the production ...

The use of kinetic models to predict oxidation performance in wastewater is limited due to fast ozone depletion during the first milliseconds of the reaction. This paper introduces the Quench Flow Module (QFM), a bench-scale experimental technique developed to measure the first 5-500 milliseconds of ozone depletion for accurate determination of ozone exposure in wastewater-ozonation processes. ...

This paper employs a parallel batch screening technique for the identification of both selective and high-affinity displacers for a model binary mixture of proteins in a cation-exchange system. A variety of molecules were screened as possible displacers for the proteins ribonuclease A (RNAseA) and alpha-chymotrypsinogen A (alpha-chyA) on high performance Sepharose SP. The batch screening data f...

We address the problem of estimating statistics of hidden units in a neural network using a method of analytic moment propagation. These statistics are useful for approximate whitening of the inputs in front of saturating non-linearities such as a sigmoid function. This is important for initialization of training and for reducing the accumulated scale and bias dependencies (compensating covaria...

This paper examines the operating characteristics of an M/G/1 retrial queueing system under Bernoulli vacation schedule with setup times. The server renders first phase of essential service (FPS) to all the arriving units whereas second phase of multi-optional services (SPS) to only some of them who demand for the same. The server may breakdown according to Poisson process in working state i.e....

This article summarizes the investigation of in-line particle characterization during high shear wet granulation (HSWG) using focused beam reflectance measurement (FBRM) for enhanced process understanding, which is part of an effort to develop this drug product within the framework of quality by design (QbD) and process analytical technology (PAT). Traditionally, the effectiveness of in-line mo...

In a video-on-demand (VOD) environment, batch-ing of requests is often applied to reduce the I/O demand and increase the availability of VOD services. This scheme, however, unfairly forces rst comers to wait for subscribers arriving late at the batch. Some of these victims may become impatient and decide to renege. To address this issue, we introduce a chaining technique which allows a client s...

Abstract. In this paper, we analyze a stochastic model representing batch fermentation in the process of glycerol bio-dissimilation to 1,3-propanediol by klebsiella pneumoniae. The stochasticity in the model is introduced by parameter perturbation which is a standard technique in stochastic population modelling. Thus, based on the nonlinear deterministic dynamical system of glycerol bioconversi...

Chip-multiprocessors (CMPs) must often execute workload mixes with different performance requirements. On one hand, user-facing, latency-critical applications (e.g., web search) need low tail (i.e., worst-case) latencies, often in the millisecond range, and have inherently low utilization. On the other hand, compute-intensive batch applications (e.g., MapReduce) only need high long-term average...