نتایج جستجو برای: based nanoparticles
تعداد نتایج: 3023409 فیلتر نتایج به سال:
germanium nanowires (genws) were synthesized using chemical vapor deposition (cvd) based on vapor–liquid–solid (vls) mechanism with au nanoparticles as catalyst and germanium tetrachloride (gecl4) as a precursor of germanium. au catalysts were deposited on silicon wafer as a thin film, firstly by sputtering technique and secondly by submerging the silicon substrates in au colloidal solution, wh...
Nanoparticles may be comprised of several kind materials being classified as nondegradable and biodegradable. Biodegradable systems have an advantage over nondegradable systems in that they are non-toxic, biotolerabl, biocompatible, biodegradable, and water-soluble. Among these systems, the role of natural polysaccharides in developing prepared nanoparticles has significantly increased (Zhang e...
There is an increasing interest in using nanoparticles, and in particular polysaccharide-based ones as carriers for the delivery of chemotherapeutic agents. They are also being investigated for enhancing their blood circulation time thereby resulting in increased therapeutic efficiency. Natural Polysaccharides as drug delivery systems, have received the most attention, owing to their benefits, ...
In this paper, we present a multi-source nanonetwork model for biomedical diagnosis applications, based on the Localized Surface Plasmon Resonance by different shape gold nanoparticles (i.e., cylinder, cube, and rod). We present the process of multi-source emission, diffusion, and reception of nanoparticles, based on the ligand/receptor binding. Then, a multi-detection process of DNA alteration...
Macromolecular prodrugs are very useful systems for achieving controlled drug release and drug targeting. In particular, various macromolecule-antitumor drug conjugates enhance the effectiveness and improve the toxic side effects. Also, polymeric micro- and nanoparticles have been actively examined and their in vivo behaviors elucidated, and it has been realized that their particle characterist...
A novel magnetic fluorescent encoded nanoimmunoassay system for multicomponent detection and separation of the subtrace pathogenic DNA (hepatitis B virus surface gene, HBV; hepatitis A virus poly the protein gene, HAV) was established based on new type of magnetic fluorescent encoded nanoparticles and sandwich immunoassay principle. This method combines multifunctional nanoparticles, immunoassa...
Targeted delivery of drugs across endothelial barriers remains a formidable challenge, especially in the case of the brain, where the blood-brain barrier severely limits entry of drugs into the central nervous system. Nanoparticle-mediated transport of peptide/protein-based drugs across endothelial barriers shows great potential as a therapeutic strategy in a wide variety of diseases. Functiona...
RNA interference technology has been widely applied in biomedical therapy in recent years. A type of small RNA molecule - siRNA could regulate the expression of disease related genes by breaking down the integrity of mRNA with high specificity. However, the low efficiency of siRNA delivery to its target seriously hampered the RNAi therapy. Compared with viral-based delivery systems, non-viral-b...
in the present study, an attempt was made to develop galactosylated albumin nanoparticles of cimetidine for treatment of acetaminophen induced hepatotoxicity. by developing the galactosylated nanoparticulated delivery of cimetidine the required action of drug at the target site i.e at liver can be provided. the advantage of targeting helps to reduce the systemic side effects which may be occur ...
We describe here a simple assay that allows the visual detection of a protease. The method takes advantage of the high molar absorptivity of the plasmon band of gold colloids and is based on the color change of their solution when treated with dithiols. We used C- and N-terminal cysteinyl derivatives of a peptide substrate exploiting its selective recognition and cleavage by a specific protease...
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