cinnamon has many therapeutic effects, such as its impact the increase of sexual ability. this experiment was conducted to determine the effect of cinnamon extract on spermatogenesis and hormonal axis of pituitary gonad in mice. the animals used in this study are male adult mice (weighing about 30-34 g and 9-10 weeks old). cinnamon was purchased from one of the most valid shops in jahrom and th...

background and objectives: acrylamide is a monomer which is formed in foodstuffs containing carbohydrates altered to asparagine during thermal processing. vitamin e is a component in human diet considered as the most effective lipid-soluble antioxidant found in the biological system. it prevents initiation of oxidative tissue damage. the aim of this study was to investigate the potential role o...

background: according benefcial effects of  tribulus terrestris  (tt) extract on  tissue damage, the present study investigated the infuence of hydroalcoholic extract of tt plant on cisplatin (cis) (ebewe pharma, unterach, austria) induced renal tissue damage in male mice. methods: thirty mice were divided into five groups (n = 6). the first group (control) was treated with normal saline (0.9% ...

background several studies showed that dopamine and norepinephrine improve retention and retrieval of memory. methylphenidate is an enhancer of dopamine and norepinephrine in brain. objectives in the present study, the effect of methylphenidate was evaluated on retention and retrieval of memory in young and aged mice using passive avoidance apparatus. materials and methods animals were divided ...

background and objective: n-methyl-d-aspartate (nmda) antagonists such as piperidines are the most important antiepileptic drugs. considering the fact that piperidine derivatives such as phencyclidine (pcp) and its new derivative, 1-[1-(3-methoxyphenyl) (tetralyl)] piperidine (pcp1), have different potencies, the antiepileptic effects of mentioned drugs were investigated in the present study. ...

in the present study the effects of both cck receptor agonists and antagonists on antinociception induced by morphine in the tail-flick test have been evaluated. m orphine induced dose-dependent antinociception in mice. the response of morphine was potentiated by sulfated cholecystokinin-8 (cck-8s) but not by unsulfated cholecystokinin-8 (cck-8u). the cck receptor antagonists mk-329 and l-365, ...

introduction: there is not much data on parasitic infections of laboratory animals that are kept in conventional conditions in iran. the present study was designed to investigate intestinal helminths infections in laboratory colonies of rats and mice. methods: droppings from 110 mice and 110 rats (each animal one dropping) belonging to experimental and breeding groups in four animal houses were...

background and objective: regarding inefficiency of common drugs used for alleviation of anxiety due to narcotics withdrawal, the present study was evaluated methadone and haloperidol co-drugs therapy on anxiety due to morphine withdrawal. materials and methods: ninety eight nmri male mice were divided into acute and chronic experimental groups. then, each group was divided into 7 subgroups: sa...

background: successful embryo transfer (et) technique is a fateful step of all efforts to achieve live births from in vitro produced embryos in assisted reproductive techniques or in knockout, transgenic or cloned animal projects. small reproductive tract of mice and limitation of current techniques may not well satisfy the requirements for mass production of genetically modified mice. genetic ...

background: there are few studies indicating the detrimental effects of ibuprofen on sperm fertility potential and dna integrity. objective: to determine the effects of ibuprofen on sperm parameters, chromatin condensation and dna integrity of mice. materials and methods: in this experimental study, 36 adult male mice with average weight 37 gr were divided into three groups, including control (...