AIMS To report circulating and mucosa-deposited anti-basement membrane zone autoantibodies in a series of six ectodermal dysplasia patients with severe bilateral cicatrising conjunctivitis and blindness due to both corneal disease and intractable surface inflammation. We also report clinical improvement with steroid-sparing systemic immunosuppression combined with clearance of bacterial colonis...

PURPOSE To compare the kinetics and speed of kill of Streptococcus pneumoniae and Haemophilus influenzae on exposure to three topical ophthalmic antibiotic solutions. MATERIALS AND METHODS Bacterial conjunctivitis isolates of S. pneumoniae and H. influenzae were exposed to 1:1000 dilutions of moxifloxacin 0.5%, tobramycin 0.3%, gentamicin 0.3%, and water (control). At 15, 30, 60, 120, and 180...

We used method of autotransplantation of macrophage cells in the treatment of purulent endobronchitis of different etiology in children. 30 patients (14 boys and 16 girls) at the age from 1 to 9 years old were examined. Bronchological investigation of patients diagnosed one-sided purulent endobronchitis. The positive dynamics of the cytological indexes and clinical symptoms have proved the effe...

OBJECTIVE To determine the trends of conjunctival sac bacterial flora isolated from patients prior to cataract surgery. SUBJECTS AND METHODS The study comprised 579 patients (579 eyes) who underwent cataract surgery. Specimens were collected by lightly rubbing the inferior palpebral conjunctival sac with a sterile cotton swab 2 weeks before surgery, and then cultured for isolation of bacteria...

Helcococcus kunzii has never been reported in veterinary medicine. The isolation of H. kunzii from a sow with purulent urocystitis is described, suggesting this organism's potential pathogenic role in swine.

Conjunctivitis, also known as pink eye, is a conjunctival inflammation. It brought on by bacteria, viruses, toxins, and allergies, including coronaviruses, the most frequent reason being allergic conjunctivitis (AC), which exposure to pollutants like pollen, animal hair, or mold. The primary contributor it linkage of immunoglobulin E caused allergens receptors stimulated mast cells. As conseque...

In a recent issue of Clinical Ophthalmology, Friedlaender and Protzko (2007) review the development and effi cacy of 1% azithromycin in DuraSite ® (AzaSite™, Inspire Pharmaceuticals , Inc., Durham, NC) for the treatment of bacterial conjunctivitis. The authors conclude that 1% azithromycin in DuraSite offers a simplifi ed dosing regimen with sustained bactericidal levels that decrease resistanc...

The aerobic microbial flora of 823 eyes with acute bacterial conjunctivitis, corneal ulceration, dacryocystitis, discharging sockets, blepharitis, and postoperative infections has been investigated. Staphylococci, Streptococcus pneumoniae, and nonfermenting Gram-negative bacilli including Pseudomonas aeruginosa were the main pathogens. Fermenting coliforms were also infrequently isolated. The l...

Moxifloxacin is a widely used topical antibiotic in various bacterial infections of the eye. Its safety and efficacy have been proved by many studies. We report a case of a rare adverse effect following its use. A 10-year-old female who had presented with acute bacterial conjunctivitis in both eyes with no corneal involvement was started on preservative-free 0.5% topical moxifloxacin four times...