نتایج جستجو برای: bacterial antigens
تعداد نتایج: 315802 فیلتر نتایج به سال:
Naturally acquired immunity against invasive pneumococcal disease (IPD) is thought to be dependent on anti-capsular antibody. However nasopharyngeal colonisation by Streptococcus pneumoniae also induces antibody to protein antigens that could be protective. We have used human intravenous immunoglobulin preparation (IVIG), representing natural IgG responses to S. pneumoniae, to identify the clas...
It was demonstrated by Keogh et al. (1947) and Warburton et al. (1949) that several products of bacterial cultures could be adsorbed to erythrocytes, which then could be agglutinated by sera containing antibodies to those bacterial antigens. This approach was developed in the case of a constituent of tuberculin by Middlebrook and Dubos (1948) and Rothbard et al. (1950). The work of the latter g...
Anaplasma phagocytophilum transmembrane and surface proteins play a role during infection and multiplication in host neutrophils and tick vector cells. Recently, A. phagocytophilum Major surface protein 4 (MSP4) and Heat shock protein 70 (HSP70) were shown to be localized on the bacterial membrane, with a possible role during pathogen infection in ticks. In this study, we hypothesized that A. p...
We applied an immunoscreening technique, in vivo-induced antigen technology (IVIAT), to identify immunogenic bacterial proteins expressed during human infection with Salmonella enterica serovar Typhi, the cause of typhoid fever. We were able to assign a functional classification to 25 of 35 proteins identified by IVIAT. Of these 25, the majority represent proteins with known or potential roles ...
As the disease caused by Mycobacterium tuberculosis continues to be a burden, there is a concerted effort to find new vaccines to combat this problem. One of the important vaccine strategies is whole bacterial vaccines. This approach relies on multiple antigens and built-in adjuvanticity. Other mycobacterial strains which share cross-reactive antigens with M. tuberculosis have been considered a...
Invasive infections caused by drug-resistant bacteria are a problem responsible for many fatal cases, especially in burn wound care centers, while bacterial resistance to antibiotics is growing dramatically worldwide. In this work, we utilize pulsed electric fields (up 25 kV/cm × 750 ns) combination with low-concentration (1%) acetic acid the inactivation of P. aeruginosa. An vivo superficial i...
Bacterial glycans are essential components of bacterial walls and crucially important cell surface antigens such as lipopolysaccharide polysaccharide capsules, which act virulence-causing factors. Polysaccharide capsules in bacteria naturally composed recurring oligosaccharides lipopolysaccharides. LPS is domains that hydrophobic nature known lipid A or endotoxin, a nonrepeating oligosaccharide...
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