A growing number of studies have reported altered functional connectivity in schizophrenia during putatively "task-free" states and during the performance of cognitive tasks. However, there have been few systematic examinations of functional connectivity in schizophrenia across rest and different task states to assess the degree to which altered functional connectivity reflects a stable charact...

Attending and responding to sound location generates increased activity in parietal cortex which may index auditory spatial working memory and/or goal-directed action. Here, we used an n-back task (Experiment 1) and an adaptation paradigm (Experiment 2) to distinguish memory-related activity from that associated with goal-directed action. In Experiment 1, participants indicated, in separate blo...

The n-back task is one of the most commonly used working memory (WM) paradigms in cognitive neuroscience. Converging evidence suggests activation lateral prefrontal cortex (PFC) and pupil dilation [a proxy for locus coeruleus (LC) activation] during this task. However, it remains unclear whether PFC LC are functionally associated performance. This study's aim was to examine relationship between...