LABORATORY DATA adrenal changes phaeochromocytoma adrenal cortex hormones adrenal insufficiency, adrenal hypoplasia aldosterone, high levels chromosomal assignment chromosome 11q localization chromosome 3p localization gene, structural-functional anomalies CCND1 (PRAD1) cyclin D1, gene chr.11q13 gene analysis-DNA analysis ST11 (PETS1), gene chr.3p25 VHL von Hippel-Lindau syndrome, gene chr.3p26...

Abstract We obtain a polynomial upper bound on the mixing time $T_{CHR}(\epsilon)$ of coordinate Hit-and-Run (CHR) random walk an $n-$ dimensional convex body, where is number steps needed to reach within $\epsilon$ uniform distribution with respect total variation distance, starting from warm start (i.e., which has density body that bounded above by constant). Our in n , R and $\frac{1}{\epsil...

Despite rapid progress in the physical characterization of murine and human genomes, little molecular information is available on certain regions, e.g., proximal mouse chromosome 11 (Chr 11) and human chromosome 2p (Chr 2p). We have localized the wobbler spinal atrophy gene wr to proximal mouse Chr 11, tightly linked to Rab1, a gene coding for a small GTP-binding protein, and Glnsps1, an intron...

INTRODUCTION Current psychosis risk criteria have often been studied on a pre-selected population at specialized clinics. We investigated whether the Structured Interview for Prodromal Syndromes (SIPS) is a useful tool for psychosis risk screening among adolescents in general psychiatric care. METHODS 161 adolescents aged 15-18 with first admission to adolescent psychiatric services in Helsin...

Genetic studies are indispensable for understanding the mechanisms by which individuals develop differences in social behavior. We report genetic mapping of social interaction behavior using inter-subspecific consomic strains established from MSM/Ms (MSM) and C57BL/6J (B6) mice. Two animals of the same strain and sex, aged 10 weeks, were introduced into a novel open-field for 10 min. Social con...

ETHNOPHARMACOLOGICAL RELEVANCE Four traditional Chinese herbal remedies (CHR) including Buyang Huanwu decoction (BHD), Xuefu Zhuyu decoction (XZD), Tianma Gouteng decoction (TGD) and Shengyu decoction (SYD) are popular used in treating brain-related dysfunction clinically with different syndrome/pattern based on traditional Chinese medicine (TCM) principles, yet their neuroprotective mechanisms...

The cerebello-thalamo-cortical circuit (CTCC) has been implicated in schizophrenia. However, this work has been limited to structural and functional networks, or behavior, and to date, has not been evaluated in clinical high-risk (CHR) youth, a group at elevated risk for psychosis. Here, we used an innovative learning paradigm known to activate the CTCC (while limiting potential motor confounds...

Mutations on NHR (N-terminal heptad repeat) associated with resistance to fusion inhibitor were observed. In addition, mutations on CHR (C-terminal heptad repeat) accompanied NHR mutations of gp41 are noted in many cases, like N43D/S138A double mutation. In this work, we explored the drug resistant mechanism of N43D mutation and the role of S138A second mutation in drug resistance. The binding ...

We introduce the notion of connuence for Constraint Handling Rules (CHR), a powerful language for writing constraint solvers. With CHR one simpliies and solves constraints by applying rules. Connuence guarantees that a CHR program will always compute the same result for a given set of constraints independent of which rules are applied. We give a decidable, suucient and necessary syntactic condi...

This volume contains the papers presented at CHR 2013, the 10th International Workshop on Constraint Handling Rules held on July 13th 2013 in Berlin (Germany), at the occasion of the Third International Summer School on CHR. This workshop is the tenth in a series of annual CHR workshops. It means to bring together in an informal setting, people involved in research on all matters involving CHR,...