The purpose of this study was to observe the antibacterial activity of aqueous methanolic extracts of 10 plants against 2-gram negative bacteria (Pasteurella multocida, Escherichia coli) and 3-gram positive bacteria (Bacillus cereus, Staphylococcus aureus, Corynebacterium bovis) by using disc diffusion method. The minimum inhibitory concentration (MIC) was determined by agar well diffusion meth...

A series of 20-deoxo-20-cyclic (alkylamino) derivatives of tylosin, desmycosin, macrocin and lactenocin was prepared by reductive amination of the C-20 aldehyde group. The majority of the compounds were prepared using metal hydrides (sodium cyanoborohydride or sodium borohydride) as the reducing agents and a suitable cyclic alkylamine. Subsequently, a more convenient procedure was developed usi...

Physiological, serological, morphological, and cultural differences were observed among 30 Pasteurella multocida cultures of human origin. The usual variations in the fermentation of glycerol, lactose, sorbitol, trehalose, and xylose were observed. Unlike most P. multocida, two cultures did not produce indol. Six serotypes were found. In addition to the widely recognized iridescent, blue, and w...

Pharyngeal swabs were collected from 298 lesser snow geese (Chen caerulescens caerulescens) at Banks Island (Northwest Territories. Canada) in the summer of 1994. Pasteurella multocida serotype 1 was isolated from an adult male bird and P. multocida serotype 3 was isolated from an adult female goose. Pathogenicity of the serotype 1 isolate was confirmed by inoculation in Pekin ducks (Anas platy...

Bacterial meningitis is a severe illness with potentially dangerous consequences in any patient population. In the years from 2003 to 2007, children less than two years old had the highest estimated rate of bacterial meningitis of any age group. [1] In neonates, not only are the risks of infection profound – including death – the presentation can be atypical, making the likelihood of occult dis...

We have recently seen an unusual case of endophthalmitis secondary to Pasteurella multocida infection. Unlike previously reported cases this patient had no previous history of animal bites or scratch wounds. Treatment included subconjunctival, parenteral, and intravitreal administration of ampicillin. Although the eye was sterilised, the patient's vision remained poor owing to the extensive amo...

A 62-year-old patient with peritoneal dialysis (PD)-associated peritonitis is described. Identical strains of Pasteurella multocida and Streptococcus minor were cultured from the dialysate, and from the saliva of her recently adopted stray cat. Pasteurella is not often encountered as pathogen in PD-associated peritonitis, Streptococcus minor has never been cultured in human infection before. We...

in order to assess the immunopathological effects of aqueous echinacea purpurea extract (epe) on mice experimentally challenged with pasteurella multocida serotype a, forty female balb/c mice were randomly divided into four groups. the groups included a control group (received sterile distilled water 2 times/week for 2 weeks, intraperitoneally and then 100 μl sterile saline intranasally), a pma...

pasteurella multocida is known as one of the main organisms causing pneumonia in sheep. as immunity in pasteurellosis is serogroup specific, identification of prevalent capsular group among endemic areas is essential. the aim of this study was to molecular identification and determine of the capsular type of the p. multocida strains isolated from sheep pneumonia in iran. bacteriological and bio...

an inactivated trivalent fowl cholera vaccine consisted of serotypes 1, 3 and 4 pasteurella multocida strains was prepared. the vaccine provided 70-100% protection against challenge with homologous starins. elisa assay showed a considerable increase in antibody titer after towice vaccination of 8 weeks chickens. it was found that the trivalent vaccine can induce immunogenic response in vaccinat...