A 5 1/2-yr-old child developed severe anemia with erythroid hypoplasia and 50% ringed sideroblasts in his bone marrow. A serum inhibitor of erythropoiesis was demonstrated, utilizing syngeneic and autologous bone marrow in a plasma-clot culture system. The IgG fraction of the patient's serum effected similar suppression of erythroid colony formation. Prednisone therapy was ineffective, but foll...

BACKGROUND Medical ozone is more bactericidal, fungicidal, and virucidal than any other natural substance. Some studies proved that ozone infused into donated blood samples can kill viruses 100% of the time. Ozone, because of its special biologic properties, has theoretical and practical attributes to make it a potent hepatitis C virus (HCV) inactivator, which suggests an important role in the ...

Serum, 2 ml, was assayed colorimetrically with the “SMA 12/60 AutoAnalyzer” (Technicon Instruments Corp., Tarrytown, N.Y. 10591). Colorimetric determination (at 45#{176}C) of AST with the SMA 12/60 is based on the coupling reaction of a diazonium salt of N-butyl4-methoxymetanilamide with oxaloacetic acid produced when AST acts on ketoglutarate. AST activity of the same serum specimen was determ...

Background: The immunologic profile of chronic urticaria is not only important for diagnostic purposes, but also for therapeutic approaches. This study evaluated the serum levels of Interleukin-6 (IL-6), Tumor Necrosis Factor-α (TNF-α) and Interferon-ϒ (IFN-ϒ) in patients with chronic urticaria to find a biomarker.Materials and Methods: Forty-one patients with chronic urticaria referring to the...

1533 salicylic acid (1-8-3 6 g/day) in hospital (figure). The two other patients had taken acetylsalicylic acid before admission and had raised serum AST concentrations, which were subsequently normal. Serum AST concentrations were affected in all, and gamma-glutamyltransferase and glutamic purpuric transaminase concentrations were also affected in four patients. All other liver function tests ...

Aim of the study was to evaluate serum levels of insulin-like growth factor binding protein-3 in patients with liver cirrhosis and to compare serum IGFBP-3 levels with other liver function tests. Fifty-one patients with liver cirrhosis were selected for our study. We measured IGFBP-3 (1.67+/-1.06 mg/l, mean+/-SD), albumin (32+/-8 g/l), prealbumin (0.22+/-0.14 g/l), AST (2.29+/-2.38 microkat/l),...

UNLABELLED Serum aminotransferase [such as aspartate aminotransferase (AST) and alanine aminotransferase (ALT)] is commonly used as an indicator of liver disease. The aim of the study was to determine the degree to which aminotransferase results are associated with increased mortality at the population level. All adult residents of Olmsted County, Minnesota, who had a health care encounter at M...

To investigate the potential role of recombinant human erythropoietin (rhEpo) in patients receiving intensive cytotoxic therapy, we measured the endogenous levels of Epo in 31 patients undergoing bone marrow transplantation (BMT). Seventeen patients underwent allogeneic BMT and 14 underwent autologous BMT. On average, 10 +/- 4 units of red blood cells (RBCs) were transfused per patient. The mea...