The authors present their experience related to the diagnosis, treatment, and followup of 431 patients with bullous pemphigoid, 14 patients with juvenile bullous pemphigoid, and 273 patients with pemphigus. The detection of autoantibodies plays an outstanding role in the diagnosis and differential diagnosis. Paraneoplastic pemphigoid is suggested to be a distinct entity from the group of bullou...

© 2010 The Authors. doi: 10.2340/00015555-0739 Journal Compilation © 2010 Acta Dermato-Venereologica. ISSN 0001-5555 Sir, Paraneoplastic pemphigus (PNP) is an autoimmune bullous disease characterized by severe mucous membrane involvement, polymorphous skin eruptions, and underlying neoplasms. Most cases are associated with lymphoproliferative neoplasms, and solid tumours have rarely been associ...

Morphea represents a localized form of scleroderma where there is predominant skin involvement, with occasional involvement of subjacent muscles. However, it usually spares the internal organs [1]. Morphea has been associated with several autoimmune diseases like mixed connective tissue disease, dermatomyositis, pemphigus, myasthenia gravis, bullous pemphigoid, systemic sclerosis, Hashimoto’s t...

BACKGROUND Bullous pemphigoid (BP) is an autoimmune blistering disease that is rare in childhood. As in adult BP, antibodies against the 180-kDa antigen (BP180) seem to be involved in the pathogenesis of the disease, but, to date, only a small number of children with the disease have been examined immunologically. OBSERVATIONS We report the cases of 4 infants with BP aged 5 to 12 months. All ...

Autoimmune vesicobullous disorders in dermatology are numerous ,the diagnosis can be helped by determining morphology of lesion, age group affected , histopathology and immunoflourescence(IF ) . Aim: The aim is to study histopathology of various Autoimmune vesicobullous disorders and its correlation with IF studies in patients attending DVL department, Guntur medical college. Material & Methods...

INTRODUCTION Bullous skin diseases, which include, among others pemphigoid, pemphigus, and dermatitis herpetiformis are classified as severe autoimmune dermatoses. It has been shown that a pattern of xenobiotic metabolism may play a role in the pathogenesis of autoimmune diseases. AIM To estimate whether the CYP2D6 genotype may be considered a predisposing factor in autoimmune bullous disease...