We examined the social skills of adults with autism, PDDNOS, and mental retardation. All participants were diagnosed with profound mental retardation. Participants in the autism and PDDNOS groups had been previously diagnosed using the Childhood Autism Rating Scale (CARS) and record review. These diagnoses were confirmed by readministering the CARS by one author and an independent rater. Social...

There are many reports about the significant roles of some amino acids in neurobiology and treatment of autism. This is a critical review of amino acids levels in autism. No published review article about the level of amino acids in autism was found. The levels of glutamate and homocystein are increased in autism while the levels of glutamine and tryptophan are decreased. Findings regarding the...

Autism has been shown to have a major genetic risk component; the architecture of documented autism in families has been over and again shown to be passed down for generations. While inherited risk plays an important role in the autistic nature of children, de novo (germline) mutations have also been implicated in autism risk. Here we find that autism de novo variants verified and published in ...

BACKGROUND Several uncontrolled studies of hyperbaric treatment in children with autism have reported clinical improvements; however, this treatment has not been evaluated to date with a controlled study. We performed a multicenter, randomized, double-blind, controlled trial to assess the efficacy of hyperbaric treatment in children with autism. METHODS 62 children with autism recruited from ...

OBJECTIVE To confirm previous evidence suggesting an association between autism and low vitamin D serum levels. METHODS This preliminary exploratory study assessed the circulating levels of 25-hydroxyvitamin D (25-OHD) in pediatric patients with autism and in typically developing controls from Juiz de Fora, Brazil. RESULTS Serum levels of 25-OHD were lower in children with autism (26.48 ± 3...

Although acupuncture has been used in the treatment of autism for many years, almost no formal clinical trials have been devoted to confirm the effectiveness of the acupuncture for the disease in the western countries, where a big population of children and family have been suffering from the shortage of effective therapy. This review is to summarize the reports from about 20 clinical trials of...

BACKGROUND Results of small trials suggest that early interventions for social communication are effective for the treatment of autism in children. We therefore investigated the efficacy of such an intervention in a larger trial. METHODS Children with core autism (aged 2 years to 4 years and 11 months) were randomly assigned in a one-to-one ratio to a parent-mediated communication-focused (Pr...

Parents of youth with neurodevelopmental disorders experience unique stressors in family functioning when compared to parents neurotypical youth. A paucity research, however, has examined differences parenting experiences across families varying disorder presentations. This paper focuses on two common and frequently co-occurring conditions: autism spectrum attention-deficit/hyperactivity (ADHD)...

The article includes a literary review of scientific works devoted to the study specific features motivational and personal sphere mothers with children diagnosed Autism Spectrum Disorder (ASD), published in number countries Africa Middle East. author describes difficulties faced by process education treatment their autistic these regions world; provides statistics on extension autism among chi...