Atopic dermatitis is a chronic inflammatory skin disease that more commonly affects children, although it is increasingly diagnosed in adults. As with other chronic skin diseases such as psoriasis, there is growing evidence that systemic processes affect an individual’s health. A recent study published in the Journal of the American Academy of Dermatology examines comorbidities in adults with a...

Interleukin (IL)-16 serves as a natural ligand of CD4 molecules and induces chemotaxis in CD4-expressing cells such as T cells, eosinophils, dendritic cells and monocytes. We examined the serum levels of IL-16 in patients with adult atopic dermatitis when their eruptions were aggravated and in non-atopic healthy controls, and then analysed the possible correlation between these values and the l...

Atopic dermatitis (atopic eczema) was the subject of the 1st Georg Rajka Symposium in Davos, on September 6 ± 9, 1998. This summary and critical review of present knowledge of atopic dermatitis, the most common chronic in ̄ammatory disease of children in industrialized countries, is aimed at physicians and nurses, researchers or students who want a brief introduction to atopic dermatitis to enab...

Adhesion molecules may play an important role in the homing of T-cell subsets into allergen-exposed skin of atopic individuals. The aim of this study was to examine the expression of adhesion molecules in atopic dermatitis skin lesions. Biopsies were obtained from lesions in 30 adult patients with atopic dermatitis and 10 healthy adults as controls. Biopsy specimens were studied by immunohistoc...

Atopic Dermatitis affects the estimated 1-5% of world population.It more than 10-20% children.Atopic Dermatitis(ad) is a chronically relapsing skin disorder with an immunologic basis The clinical presentation varies from mild to severe.In worst cases,atopic dermatitis may interfere normal growth and development.The etiopathological study eczema reveals factors psychosomatic nature disease assoc...

The T allele of rs7927894 (at 11q13.5) was associated with atopic dermatitis and other allergic diseases. Our purpose was to replicate the association with allergic phenotypes and explore the role of rs7927894 in predisposing to persistent allergic rhinitis and atopic asthma. We also wanted to explore if other SNPs at 11q13.5 contributed to effect of rs7927894. We studied patients with atopic d...

OBJECTIVES To determine whether early infectious diseases could explain the association between number of siblings and other markers of microbial exposure and the development of atopic dermatitis before the age of 18 months. DESIGN Cohort study. Information on atopic dermatitis, infectious diseases occurring before 6 months of age, number of siblings, early day care, pet keeping, farm residen...

Atopic dermatitis is a multifactorial, chronic relapsing, inflammatory disease, characterized by xerosis, eczematous lesions, and pruritus. The latter usually leads to an "itch-scratch" cycle that may compromise the epidermal barrier. Skin barrier abnormalities in atopic dermatitis may result from mutations in the gene encoding for filaggrin, which plays an important role in the formation of co...

INTRODUCTION Inflammation is an established component of cardiovascular disease (CVD) and an underlying factor of several dermatologic conditions including rosacea, atopic dermatitis, and psoriasis. Identifying potential associations between these dermatologic and cardiovascular diseases can better inform holistic healthcare approaches. The objective of this study was to determine whether rosac...

The fermentation of natural plants has a favorable effect on the functional and biological activities of living systems. These include anti-oxidative, anti-inflammatory, and anti-platelet aggregation activities. This is attributed to the chemical conversion of the parent plants to functional constituents, which show more potent biological activity. In our study, rice bran along with oriental me...