نتایج جستجو برای: atll
تعداد نتایج: 284 فیلتر نتایج به سال:
Human T-cell leukemia virus (HTLV)-1 is a human retrovirus and the etiological agent of adult T-cell leukemia/lymphoma (ATLL), a fatal malignancy of CD4/CD25+ T lymphocytes. In recent years, cellular as well as virus-encoded microRNA (miRNA) have been shown to deregulate signaling pathways to favor virus life cycle. HTLV-1 does not encode miRNA, but several studies have demonstrated that cellul...
Abbreviations: ATLL, adult T-cells leukemia-lymphoma; BAL, bronchoalveolar lavage; bp, base pair; DLco, pulmonary diffusing capacity for carbon monoxide; HAB, HTLV-I associated bronchopneumopathy; HABA, HTLV-I associated bronchiolo-alveolar disorder; HAM, HTLV-I associated myelopathy; HTLV-I, human Tcell lymphotropic virus type I; LDH, lactic acid dehydrogenase; PBMC, peripheral blood mononucle...
objective(s):htlv-1 is the first human retrovirus that has been recognized and is associated with ham/tsp and atll. studies have shown that less than five percent of htlv-1 infected carriers develop ham/tsp or atll and about ninety-five percent remain asymptomatic. therefore, the proviral load with tax may affect cellular genes such as cytokines and oncogenes, as well as involve in pathogenicit...
We describe a new rat immunoglobulin M monoclonal antibody (CH-F42) that recognizes a subset (1.5% to 8%) of normal peripheral blood T lymphocytes. The phenotype of these cells was determined, using dual-color immunofluorescence, to be CD2+, CD3'. CD4'. CD5'. CD7-, CD8-. They do not express T-cell activation markers, and are positive for UCHLl (CD46RO). but negative for 2H4 (CD45RA). The antige...
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