common carotid intima-media thickness measured with echotracking: relation with risk factors. Eur Heart J 2013;34:2368–2380. 28. O’Leary DH, Bots ML. Imaging of atherosclerosis: carotid intima-media thickness. Eur Heart J 2010;31:1682–1689. 29. Stafford M, Black S, Shah I, Hardy R, Pierce M, Richards M, Wong A, Kuh D. Using a birth cohort to study ageing: representativeness and response rates i...

PURPOSE The choice of initial anti-epileptic drug (AED) for elderly and younger adult patients with newly diagnosed epilepsy was assessed. METHODS The pattern of initial prescription of AEDs between 2000 and 2013 was retrospectively studied in two community-dwelling cohorts, identified from the case records of Kuopio University Hospital (KUH): elderly subjects (aged 65 or above at the time of...

The story of how Alma-Ata and Primary Health Care gained the attention of the world’s health leadership must be seen as one of the most intriguing in the history of health and development. The postcolonial years in the developing world saw health care that was largely hospital-based and curative in its orientation, whichmeant, of course, that most people who needed health care had little or no ...

The Lut Block (Eastern Iran) extends over 900 km in a north-south direction and is only 200 km wide in an east-west direction. It is confined by the Nayband fault and Shotori Range on the west. The eastern edge is bordered by the Sistan suture zone and Nehbandan Fault. The northern termination of Lut Block is the depression of Kavir-e-Namak and the Great Kavir Fault. The Makran arc, including ...

We have been investigating the use of low-cost, commodity components for multi-terabyte SQL Server databases [SQL]. Dubbed storage bricks, these servers are white box PCs containing the largest ATA drives, value-priced AMD or Intel processors, and inexpensive ECC memory. One issue has been the wiring mess, air flow problems, length restrictions, and connector failures created by seven or more p...

Aurintricarboxylic acid (ATA) was found to be a very potent inhibitor of purified rabbit liver phosphofructokinase (PFK), giving 50% inhibition at 0.2 microM. The inhibition was in a manner consistent with interaction at the citrate-inhibitory site of the enzyme. The data suggest that inhibition of PFK by ATA was not due to denaturation of the enzyme or the irreversible binding of inhibitor, si...

ATAs engineered for having an enlarged small binding pocket were applied the synthesis of enantiomerically pure (R)-benzo[1,3]dioxol-5-yl-butylamine, a chiral component human leukocyte elastase inhibitor DMP 777 (L-694,458). Kinetic resolution racemic amine was performed by using L59A variant (S)-selective ATA from Chromobacterium violaceum (Cv-ATA), providing residual (R)-enantiomer in excelle...

Title of thesis: PHYLOGENETIC ANALYSIS OF SWINE INFLUENZA VIRUSES ISOLATED FROM HUMANS IN ALMA-ATA, KAZAKHSTAN. Rangarajan Padmanabhan, Master of Science, 2009. Thesis directed by: Associate Professor Dr.Daniel Perez, Department of Veterinary Medicine, VA-MD Regional College of Veterinary Medicine, The University of Maryland, College Park. Continuous surveillance of influenza becomes important ...