PURPOSE The goal of this study is to assess the interactions among alcohol consumption, cigarette smoking, and aspartate aminotransferase (AST) / alanine aminotransferase (ALT) ratios on esophageal cancer. MATERIALS AND METHODS Alcohol and the risk of incidence and death from esophageal cancer were examined in a 14-year prospective cohort study of 782,632 Korean men, 30 to 93 years of age, wh...

The activity of aspartate aminotransferase (AST) in human serum has been widely determined as a diagnostic aid in liver disease. In this study, the effect of aluminium on AST isoenzymes in relation to aluminium intoxified patients has been investigated. Using gel filtration chromatography technique with Sephacryl S-300, mitochondrial aminotransferase (m-AST) and cytosolic aminotransferase (c-AS...

Submit Manuscript | http://medcraveonline.com Abbreviations: AIA: Adjuvant-Induced Arthritis ; AST: Aspartate Amino Transferase; BSA: Bovine Serum Albumin; DON: 6-Diazo5-Oxo-L-Norleucine; DRG: Dorsal Root Ganglia; GLU: Glutamate; GLS: Glutaminase; IR: Immunoreactivity; MRNA: Messenger RNA; NSAID: Non-Steroidal Anti-Inflammatory Drug; PBS: Phosphate Buffered Saline; PBST: Phosphate Buffered Sali...

Abbreviations: NAFLD, nonalcoholic fatty liver disease; NASH, nonalcoholic steatohepatitis; NAS, NAFLD activity score; ALT, alanine aminotransferase; GGT, γ-glutamyl transpeptidase; BMI, body mass index; AST, aspartate aminotransferase; CK-18, cytokeratin 18; sFas, soluble Fas; AUC, area under curve Corresponding author: Chang Wook Kim Department of Internal Medicine, Uijeongbu St. Mary’s Hospi...

Hepatitis B virus (HBV) infection is one of the important challenges facing world. The persistence or clearance HBV often determined by host's immune responses. current study was conducted during June-October 2018 on 80 patients with chronic and 96 age- gender-matched healthy controls. results showed that most were males (62.5%) while females constituted 37.5%. patients' serum positive for anti...

objective(s): the aim of the present study is to determine the effect of chloramphenicol (cap) on rat liver and small intestine. effect of phenobarbital (pb) on cap toxicity was also investigated.   materials and methods:   rats were received cap at doses of 0, 200, 400 and 600 mg/kg. another group was pretreated with 80 mg/kg pb 30 min prior to administration of various doses of cap. the exper...

Fish are continuously exposed to multiple environmental stressors that work cumulatively and synergistically. This study assessed the stress responses of Indian major carps (IMCs) cultured in a sewage-fed pond (SP) East Kolkata Wetland (EKW), India compared with normal situ. The experiment was conducted two farms Labeo rohita, Catla catla Cirrhinus mrigala for seven months, covering summer wint...

Background: Antibiotics are increasingly being prescribed during pregnancy. Even though safe non-teratogenic drugs prescribed, due to altered pharmacokinetics pregnancy can have adverse effects on hepatic metabolism. Methods: This was a prospective analytical study conducted in the department of obstetrics and gynecology at ESIC Medical College PGIMSR, Bengaluru, Bengaluru from August 2022 Janu...

The sensitivity of African amphibians Amietophrynus maculatus and Ptychadena pumiliowere exploited in determining oxidative stress induced by heavy metals pollution selected areas Lagos state.Lead (Pb), cadmium (Cd), manganese (Mn), chromium (Cr), zinc (Zn) Nickel (Ni) which is one the factors that contribute to amphibian population decline.The mean levels Total protein (TP), Aspartate Aminotra...

Background: Hepatotoxicity is one of the most important side effects anticonvulsant drugs. This study compared hepatotoxicity sodium valproate, carbamazepine, phenytoin, lamotrigine, and vigabatrin in male rats. Methods: Based on results, 56 rats were randomly divided into seven groups eight treated intraperitoneally for four weeks. Groups 1 2 received 500 mg/kg carbamazepine 3, 4, 5 injected w...