OBJECTIVE This article provides an analysis of the use of artificial sweeteners, caffeine, and excess fluids in patients diagnosed with anorexia nervosa (AN). METHOD Seventy participants with AN were recruited to participate in an ecologic momentary assessment study which included nutritional analysis using the Nutrition Data Systems for Research, a computer based dietary recall system. RES...

Aspartame (N-aspartyl-phenylalanine methyl ester), a widely used artificial sweetener, is hydrolyzed in the intestinal lumen to methanol and to its constituent amino .acids phenylalanine and aspartic acid. Ingestion of this sweetener causes a sharp increase in plasma phenylalanine I vels in normal persons. and in patients with phenylketonu ia.2The label on aspartame-containing products includes...

Detection thresholds for NaCl, KCl, sucrose, aspartame, acetic acid, citric acid, caffeine, quinine HCl, monosodium glutamate (MSG) and inosine 5'-monophosphate (IMP) were assessed in 21 young (19-33 years) and 21 elderly (60-75 years) persons by taking the average of six ascending two-alternative forced choice tests. A significant overall effect was found for age, but not for gender. However, ...

A new, simple normal phase high performance liquid chromatographic method was developed for the analysis of aspartame in tabletop sweeteners. The method is based on the derivatization of aspartame with 2, 4-dinitrofluorobenzene followed by detection at 332 nm. Separation was carried on silica column with hexane: ethyl acetate (60: 40, V/V) as mobile phase (pH was adjusted to 4.5 using 1% acetic...

This paper presents two high performance liquid chromatographic (HPLC) methods used for the separation and determination of artificial sweeteners aspartame, acesulphame K, sodium saccharin, and sodium cyclamate in beverages and special nutritional products (special food intended for specific population groups). All four compounds are soluble in aqueous solutions and can easily be separated and ...

The European Food Safety Authority (EFSA) has been asked by the European Commission to assess the carcinogenicity study performed by the European Ramazzini Foundation of Oncology and Environmental Sciences (ERF) on the artificial sweetener aspartame, which was reported in publications in 2005 and 2006. The ERF considered that the results of their study indicate that aspartame is a ‘multipotenti...

Aspartame and alitame are a type of food additives commonly used in recent years. However, it is difficult to con-clude that long-term use synthetic sweeteners completely harmless. This study aimed establish simple high performance liquid chromatography (HPLC) method detect these two sweeteners, measure the concentrations dairy products milk-containing beverages Chinese market. In this experime...

A series of photolabile o-nitrobenzyl derivatives of serotonin (caged serotonin) were synthesized: the amine-linked serotonin derivatives N-(2-nitrobenzyl) serotonin (Bz-5HT) and N-(alpha-carboxy-2-nitrobenzyl) serotonin (N-CNB-5HT), and O-alpha-carboxy-2-nitrobenzyl) serotonin (O-CNB-5HT), which has the caging group attached to the phenolic OH group. All the derivatives released free serotonin...