Multiple sclerosis (MS) most commonly affects individuals of Northern European descent who live in countries at high latitude. The relative contributions of ancestry, country of birth and residence as determinants of MS risk have been studied in adult MS, but have not been explored in the pediatric MS population. In this study, we compare the demographics of pediatric- and adult-onset MS patien...

The Himalayan Mountain Belt and adjacent Tibetan Plateau (Figure 1) remain the world’s foremost natural laboratory for investigation of continental collisional tectonics. The continuing debate over how the Asian continent has responded to the embedding of the Indian subcontinent has variously revolved around concepts such as distributed shortening (e.g. Dewey and Burke, 1973), wholesale contine...

The human RRM2P4 pseudogene has a pattern of nucleotide polymorphism that is unlike any locus published to date. A gene tree constructed from a 2.4-kb fragment of the RRM2P4 locus sequenced in a sample of 41 worldwide humans clearly roots in East Asia and has a most-recent common ancestor approximately 2 Myr before present. The presence of this basal lineage exclusively in Asia results in highe...

This article analyzes the formation of multiple and hybird identities an immigrant in Korean American writer Chang-rae Lee's Native Speaker (1995). Growing up between ancestry surrounding, second-generation Henry feels uncertainty dilemma his sense belonging. He simultaneously travels both cultural spaces quest At times, he attempts to identify himself with space along White wife. However, reac...

the two discourses with a focus on reza davari ardekani and abdolkarim soroush, were formed in iran’s society. soroush’s discourse, with religious interests influenced by islamic sources, poper’s philosophy of science, logic and epistemological accuracies of analytical philosophy and consciously liberalism, is looking for compatibility with modernity. the second discourse on reza davari ardakan...

The hemoglobinopathies encompass a heterogeneous group of disorders associated with mutations in both the alpha-globin and beta-globin genes. Non-sickling disorders are found primarily in individuals of Mediterranean, Asian and Southeast Asian ancestry. With rapid growth in the Asian and Hispanic segments of the US population, the geographic distribution of hemoglobinopathies is expected to bec...