Motivation: Expression quantitative trait loci (eQTL) studies have discovered thousands of genetic variants that regulate gene expression, enabling a better understanding of the functional role of non-coding sequences. However, eQTL studies are costly, requiring large sample sizes and genome-wide genotyping of each sample. In contrast, analysis of allele-specific expression (ASE) is becoming a ...

Previous studies by us and other groups characterized protein expression variation following long-term moderate training, whereas the effects of single bursts of exercise are less known. Making use of a proteomic approach, we investigated the effects of acute swimming exercise (ASE) on protein expression and carbonylation patterns in two hind limb muscles: the Extensor Digitorum Longus (EDL) an...

Backround: The present study has been carried out to evaluate the radio-protective effects of Alstonia scholaris extract (ASE) on peripheral blood of mice. Materials & Methods: Male Swiss albino mice were selected from an inbred colony and assorted into 4 groups. Animals in Group I were administered with double distilled water (DDW), volume equal to ASE, by oral gavage to serve as vehicle treat...

Article history: Received on: 04/08/2014 Revised on: 15/08/2014 Accepted on: 22/09/2014 Available online: 30/10/2014 The essential oils were prepared from Aster spathulifolius (ASE) and Vitex rotundifolia (VRE) by hydrodistillation and their chemical compositions were investigated by GC–MS. Analysis of ASE provided 15 components and eight of which were identified sesquiterpene compounds. The ma...

In this paper, we investigate the effects of gamma (γ) radiation on the spectral and mplified spontaneous emission (ASE) properties of two conjugated polymers (CPs) viz., poly [2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH–PPV) (CPM) and poly{[2-[2′, 5′-bis(2”-ethylhexyloxy)phenyl]-1,4-phenylenevinylene]-co-[2-methoxy-5-(2′-ethylhexyloxy)-1,4phenylene vinylene]} (BEHP-co-MEH–PPV) (B...

Ambitious targets for aggregate throughput, energy efficiency and ubiquitous user experience are propelling the advent of ultra-dense networks. Intercell interference and high energy consumption in an ultra-dense network are the prime hindering factors in pursuit of these goals. To address the aforementioned challenges, in this paper, we propose a novel user-centric network orchestration soluti...

This paper studies the asymptotic properties of area spectral efficiency (ASE) of a downlink cellular network in the limit of very dense base station (BS) and user densities. This asymptotic analysis relies on three assumptions: (1) interference is treated as noise; (2) the BS locations are drawn from a Poisson point process; (3) the path loss function is bounded above satisfying mild regularit...

MOTIVATION In the past decade, a number of technologies to quantify allele-specific expression (ASE) in a genome-wide manner have become available to researchers. We investigate the application of single-nucleotide polymorphism (SNP) microarrays to this task, exploring data obtained from both cell lines and primary tissue for which both RNA and DNA profiles are available. RESULTS We analyze d...

Changes in the morphology of rat liver mitochondria brought about by different methods of isolation and the concomitant changes in ATP-ase activity were studied. The morphology was investigated with the electron microscope. It was found that the ATP-ase activity of the isolated mitochondria cannot be readily correlated with the morphology of the mitochondria. The ATP-ase found in these preparat...

The present study was designed to investigate the anti-cancer effects of Sea hare eggs (SE) in U937 cells and its major active components. The aqueous extract of SE (ASE), which contained the highest protein content, dose-dependently inhibited the cancer cell's growth (IC50 value, 10.42 ± 0.5 µg/mL). Additionally, ASE markedly caused DNA damage by inducing apoptotic body formation, DNA fragment...