Increased production of superoxide anion may contribute to impaired bioactivity of endothelium-derived nitric oxide in hypertension. Ascorbic acid is capable of scavenging superoxide anion; however, experimental studies have shown that high physiological concentrations (>1 mmol/L) of ascorbic acid are required to prevent superoxide-mediated vascular dysfunction. To seek kinetic evidence that su...

Abstract In this study ameliorative effects of ascorbic acid (0.5 mM) on onion (Allium cepa L. cv. Red Azarshahr) under copper stress (Cu: 6.5 μM) were studied. Fresh weights of leaves and roots were reduced in seven week old plants under excess copper condition. Cu stress also reduced membrane stability index in leaves. There was a considerable increase in H2O2 content and lipid peroxidation i...

Ascorbic acid is one of the antioxidant compounds widely used against free radical stress. The present study was undertaken to examine whether ascorbic acid and hydrogen peroxide (H2O2), alone or in combination, could influence cell viability. The murine neuroblastoma cell line, N2a, was used to perform a dose response curve for ascorbic acid. It was observed that ascorbic acid alone at physiol...

Many factors can affect wheat gluten properties and functionality. One of the most important, of these factors, is wheat bug damages. Insect injects a salivary proteinase into wheat kernel that results a significant weakening effect on the gluten, in substantial losses in physical quality, dough properties and baking performance. Bread baked with the insect – damaged flour had poor quality and ...

Previous studies have shown that L-ascorbic acid is extensively oxidized to respiratory CO? in rats (1, 2) and guinea pigs (3, 4). However, little information is available on the intermediates involved in the metabolism of the vitamin. In the present study experiments carried out with carboxyland uniformly labeled L-ascorbic acid point to the presence in rat kidney of an active enzyme system fo...

An outstanding characteristic of the enzymatic oxidation of ascorbic acid by highly purified preparations of ascorbic acid oxidase, is the pronounced inactivation of the enzyme that occurs during the course of the reaction (1). I t is the purpose of this communication to present data showing that the enzyme inactivation occurring during the reaction, is due to causes which, for the purposes of ...

introduction the cryopreservation of spermatozoa has provided special opportunities for the preservation of genetic resources and improving breed programs by the artificial insemination technique (holt, 1996). sperm cryopreservation stimulates intracellular ice crystals formation, increasing osmotic and chilling injury that causes sperm cell damage (isachenko et al. 2003). freezing and thawing ...

Ascorbic acid (vitamin C) has major effects on the intestinal uptake and utilisation of Fe in humans. The objective of the present study was to investigate the impact of Fe on the acquisition of ascorbic acid. The strategy was to study the cellular uptake and transport of ascorbic acid in the presence of Fe and also to observe the expression of the Na-dependent vitamin C transporter 1 (SVCT1) p...

Introduction: Ascorbic acid (AA) acts as an antioxidant in the Central nervous system (CNS) of the mammalians. It is released from the some nerve ending together with neurotransmitters. The results have shown that Ascorbic acid could affect learning as well as memory. In this study, we examined the effect of ICV injection of ascorbic acid on learning and memory by Morris water maze. Method: In...

Determinations of the concentration of ascorbic acid in whole blood (1, 2, 3, 4, 5, 6, 7, 8) and in plasma or serum (9, 10, 11, 12, 13, 14, 15, 16, 17, 18) as well are believed to indicate the degree of saturation of the organism. No strict correlation, however, has been established between the ascorbic acid content of whole blood and of plasma, although the concentration in cells is consistent...