UNLABELLED The testis descends in two phases. Animal studies suggest, that the transabdominal descent of the testis depends on the insulin-like hormone 3 (INSL3). Androgens are important in the inguinoscrotal testicular descent in animals and humans. In general, the cause of cryptorchidism is unknown and the aetiology is possibly multifactorial. Histological changes in cryptorchid testes demons...

background: given the paucity of data on possible testis changes in opioid dependents, we sought to compare the testis volumes between a group of opium dependents and a group of healthy controls. objective: comparison of testis volume between opium dependents and healthy controls. materials and methods: this case-control study recruited 100 men with opium dependency (cases) and 100 healthy men ...

Unilateral orchidectomy (UO) is required when further breeding potential is important. It is sometimes necessary to remove a single testis in a matured stallion for therapeutic reasons. In this study, twelve donkeys were used to evaluate three techniques of unilateral castration, histological and morphological changes on the remaining testis. Results of the study showed that each of the surgica...

Background The present study describes the susceptibility of prepubertal testis of mice to prooxidant induced oxidative impairments both under in vitro and in vivo exposure conditions. MaterialsAndMethods Following in vitro exposure to iron (5,10 and 25 M), oxidative response measured in terms of lipid peroxidation and hydroperoxide levels in testis of pre pubertal mice (4 wk) was more robust c...

mycotic pseudoaneurysm of the ascending aorta is rare in patients undergoing coronary artery bypass graft (cabg) and usually caused by staphylococcus aureus. we describe a patient with a mycotic pseudoaneurysm of the ascending aorta at the proximal vein graft anastomosis site after cabg. culture from the sinus tract of the sternum and from the aneurysm sac was klebsiella pneumoniae. surgical te...

Identification of genes specifically expressed in adult and fetal testis is important to further our understanding of testis development and function. In this study, a novel SMYD3 transcript variant, termed SMYD3-NY (GenBank Accession No. AY186742), was identified by hybridization of adult and fetal human testis cDNA probes with a human cDNA microarray. SMYD3-NY transcript was expressed at 2.3-...

In vivo effects of prostaglandin D2 (PGD2) on rat testicular testosterone levels were studied. Testosterone levels were determined by HPLC after 6 hours of PGD2 and of hCG. The testosterone levels were decreased by dose of 500 micrograms/rat intraperitoneal injection. Testis testosterone levels were subsequently decreased by intratesticular injection with PGD2 (1.0 micrograms) into the right te...

abstract objective: previous studies have indicated the hyperglycemia-induce cell death in various tissues such as brain, kidneys, liver and especially in the testis. recent studies have reported that diabetes can trigger male infertility. in this study we report the histological analysis of the testis tissue after diabetes type 1 induction in wistar rats. materials and methods: at various time...

testicular chloroma is an unusual form of extramedullary acute myeloid leukemia. we present a rare case that after chemotherapy relapsed with the appearance of metachronous testicular chloroma and we suggest prophylactic radiotherapy.

conclusions buprenorphine is more suitable for treating opiate addiction in males since it does not affect normal testicular structure and function. results stereological analysis of rat testes showed no significant effect of methadone and buprenorphine administration on the testis volume (p > 0.05). however, microscopic stud­ies of rat tissues in the methadone-administered group showed atrophi...