Cardiac arrhythmias are a major cause of morbidity and mortality across the world. Learning the science behind the use of antiarrhythmic drugs is essential for all medical graduates. However, many antiarrhythmic drugs are available, and most of them have complex pharmacodynamic and pharmacokinetic profiles. We tried to improvise our teaching by conducting interactive, worksheet-based, small-gro...

Epigenetic silencing of tumor suppressor genes (TSGs) is considered a significant event in the progression of cancer. For example, EPB41L3, a potential biomarker in cervical cancer, is often silenced by cancer-specific promoter methylation. Artificial transcription factors (ATFs) are unique tools to re-express such silenced TSGs to functional levels; however, the induced effects are considered ...

In this work multiple linear regression (MLR) and artificial neural network (ANN) were used to predict the retention factors of 40 basic and neutral drugs in immobilized artificial membrane liquid chromatography. Two separate models were developed for prediction of solute retention in two mobile phase compositions which were used five identical descriptors. The standard errors in ANN calculatio...

pharmacists are healthcare professionals who practice in pharmacy, the field of health sciences focusing on safe and effective medication use. the role of pharmacist has shifted from the classical “lick, stick and pour” dispensary role, to being an integrated member of the health care team directly involved in patient care. but, in our country pharmacists are mainly engaged with manufacturing o...

Purpose: To evaluate the erosive effect of pediatric liquid medicinal syrups on primary and permanent enamel. Materials methods: Eighty teeth were equally divided into eight subgroups (n=10), according to immersion solutions: Depakine, Ventolin, Sansovit, Artificial saliva. The cycles drugs conducted under a 1-min agitation three times daily for 28 days. Enamel microhardness measurements taken ...

This paper examines Yilmaz, Ören and Aghaee's outline of present research efforts into the development of simulations that " represent the behavior of active (human) entities in the world. " The paper argues that the Carter-Bostrom formulation of the anthropic principle provides a more functional set of theoretical, and pragmatic proposals to frame the issue of the simulation of human sociocogn...

This paper examines negotiation as a means of conflict resolution among participants involved in the design, manufacture and assembly process of designing connections in buildings. A distributed problem-solvlng (DPS) architecture which models participants as semi-autonomous computer "agents" which reason from their perspectives during design evaluation is presented. The system, called the Desig...

This paper presents two consecutive constraint representation and processing systems for artificial intelligence applications. The main aim of the two systems is to provide powerful knowledge representation facilities in the form of constraints. The facilities taken into account include generic constraints, parameterization, hierarchization, a specialized language for declaring the functionalit...