Chronic arsenic exposure causes vascular diseases associated with systematic dysfunction of endogenous nitric oxide. Replacement of heavily arsenic-contaminated drinking water with low-arsenic water is a potential intervention strategy for arsenosis, although the reversibility of arsenic intoxication has not established. In the present study, we examined urinary excretion of cyclic guanosine 3 ...

Humans have had a long and tumultuous relationship with heavy metals. Their ubiquitous nature and our reliance on them for manufacturing have resulted at times in exposures sufficient to cause systemic toxicity. Their easy acquisition and potent toxicity have also made them popular choices for criminal poisonings. This article examines the clinical manifestation and pathophysiology of poisoning...

Widespread arsenic contamination of mining wastewater of Zarshouran (West Azerbaijan province) has led to a massive epidemic of arsenic poisoning in the whole of surrounding areas. It is estimated that approximately all agriculture fields are being irrigated with the water that its arsenic concentrations elevated above the World Health Organization’s standard of 10 parts per billion. A novel ad...

Residents of the Pingtung Plain, Taiwan, use groundwater for drinking. However, monitoring results showed that a considerable portion of groundwater has an As concentration higher than the safe drinking water regulation of 10 μg/L. Considering residents of the Pingtung Plain continue to use groundwater for drinking, this study attempted to evaluate the exposure and health risk from drinking gro...

Sir,?S, a Hindu, male, aged 38, consulted me for dark pigmented spots on the palms. Syphilis was suspected, and the Wassermann gave a positive reaction. Anti-syphilitic treatment was commenced with 0.3 gramme of neosalvarsan, for the first injection. Ten minutes after the fifth injection (0.45 gramme of neosalvarsan) there was a thin discharge of serous fluid from the palms, something akin to b...

then again there is the Bravo case, and those of Cook, llcMullan and Winslow, and lastly, the more'recent cases of Palmer and Klosowski. Poisoning by salts of antimony has occasionally been recorded in India, but it is usually spoken of as a rare occurrence in this country Is this really the fact, and lias arsenic such an absolute monopoly for criminal purposes as is generally believed ? Althou...