Putative receptors for arginine-vasopressin (AVP) in rat brain were localized and characterized using autoradiographic and radioligand-binding techniques. When brain slices were incubated with tritium-labeled vasopressin, an intense concentration of binding sites was identified which included the medial aspects of the amygdala. Binding of labeled AVP to membrane preparations from this brain reg...

The preparation of tissue, the composition of the incubating media, and the analytical techniques used in this study have all been reported in previous publications from this laboratory (l-3). We are indebted to Professor V. duvigneaud for the generous supplies of the two purified neurohypophyseal hormones used in this study, oxytocin (ON-5) and arginine-vasopressin (AVN-3). The commercial vaso...

OBJECTIVE To assess whether plasma endothelin, adrenaline, noradrenaline, arginine vasopressin, adrenocorticotropin, and cortisol concentrations were higher during cardiopulmonary resuscitation in patients in whom resuscitation was successful than in those in whom it failed, and to measure the concentrations of these hormones in the immediate post-resuscitation phase. DESIGN Prospective, desc...

Abstract Arginine vasotocin (AVT) and its homolog arginine vasopressin (AVP) modulate social behavior, including communication. In anuran amphibians, male-male competition female mate choice rely heavily on acoustic signaling. Behavioral experiments show that AVT influences motivation to call vocal production. It may also influence how males process respond socially relevant auditory stimuli, b...

Kauli, R., and Laron, Z. (1974). Archives of Disease in Childhood, 49, 482. A vasopressin analogue in treatment of diabetes insipidus. Six children, 3 adolescents, and 3 adults with vasopressin-sensitive diabetes insipidus were treated with a vasopressin analogue, DDAVP (1-deamino-8-D-arginine vasopressin), at a daily dose ranging from 5 to 20 ,ug administered twice a day intranasally. The peri...

For nearly 60 years, we have known that the brain plays a pivotal role in regulating the osmolality of body fluids. Over this time period, scientists have determined the structure and function of arginine vasopressin and its receptors, the role of the posterior pituitary as a storage site, and the determinants of vasopressin release. The cellular mechanisms by which the kidney responds to vasop...

1. The role of vasopressin in blood pressure control and in the pathogenesis of one-kidney Goldblatt hypertension in the conscious dog was investigated. 2. Infusion of synthetic arginine vasopressin to elevate plasma levels approximately five-fold caused bradycardia in normal dogs and increase in mean arterial blood pressure in dogs with pharmacological autonomic blockade. 3. A similar degree o...