Article history: Received 23 September 2010 Received in revised form 7 April 2011 Accepted 16 May 2011 Available online 23 May 2011

Article history: Received 12 September 2013 Received in revised form 8 April 2014 Accepted 3 July 2014 Available online 15 July 2014

Article history: Received 8 April 2013 Received in revised form 2 September 2013 Accepted 21 January 2014 Available online 23 January 2014 Communicated by V. Rijmen

Lignans of Forsythia spp. are essential components of various Chinese medicines and health diets. However, the seasonal alteration in lignan amounts and the gene expression profile of lignan-biosynthetic enzymes has yet to be investigated. In this study, we have assessed seasonal alteration in amounts of major lignans, such as pinoresinol, matairesinol, and arctigenin, and examined the gene exp...

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