BACKGROUND AND PURPOSE The purpose of the study was to evaluate the effect of APOE genotype and the feasibility of administering an apolipoprotein E-mimetic therapeutic to modify outcomes in a murine model of intracerebral hemorrhage. METHODS Intracerebral hemorrhage was induced via stereotactic injection of 0.1 U Clostridial collagenase into the left basal ganglia of wild-type and apolipopro...

etar Alaupovic, an internationally renowned biochemist and lipidologist, died on January 30, 2014, in Oklahoma City at the age of 91 years. Dr Alaupovic was a founder of the modern field of lipoproteins whose ideas continue to have an impact on its development. He performed research and taught at Oklahoma Medical Research Foundation since 1960. In 1964, Dr Alaupovic, known to his colleagues as ...

Background and Aims: Apolipoprotein B (apoB)-containing triglyceride-rich lipoproteins low-density (LDL) are each causal for myocardial infarction atherosclerotic cardiovascular disease; however, the relative importance is unknown. We tested hypothesis that same number of apoB-containing particles from smaller LDL through to larger lipoproteins, risk similar.