INTRODUCTION Obstructive sleep apnea causes changes in normal sleep architecture, fragmenting it chronically with intermittent hypoxia, leading to serious health consequences in the long term. It is believed that the occurrence of respiratory events during sleep, such as apnea and hypopnea, can impair the transmission of nerve impulses along the auditory pathway that are highly dependent on the...

BACKGROUND Obstructive sleep apnea occurs as a result of increased collapsibility of the upper airway. Overnight fluid displacement from the legs to the neck causes pharyngeal narrowing and increased apnea severity. Sodium intake is associated with apnea severity. We hypothesized that interventions that decrease bodily fluid content might reduce the severity of sleep apnea. METHODS/DESIGN Thi...

About one half of patients who have essential hypertension have obstructive sleep apnea, and about one half of patients who have obstructive sleep apnea have essential hypertension. A growing body of evidence suggests that obstructive sleep apnea is a major contributing factor in the development of essential hypertension. Despite many patients with obstructive sleep apnea having clear symptoms ...

INTRODUCTION Obstructive sleep apnea syndrome has a high prevalence among adults. Cephalometric variables can be a valuable method for evaluating patients with this syndrome. OBJECTIVE To correlate cephalometric data with the apnea-hypopnea sleep index. METHODS We performed a retrospective and cross-sectional study that analyzed the cephalometric data of patients followed in the Sleep Disor...

OBJECTIVE A new oral appliance to treat obstructive sleep apnea in infants with Pierre Robin sequence has recently been shown to be superior to a sham procedure. We now investigate safety and long-term effects of this appliance on obstructive sleep apnea in infants with Pierre Robin sequence. DESIGN Case series with repetitive follow-up examinations. SETTING Tertiary neonatal intensive care...

Introduction: Obstructive sleep apnea (OSA) is a highly prevalent sleep-disordered breathing (SDB).   Case Report: Two 53- and 51-year-old male cases with daytime sleepiness and opium abuse and severe sleep apnea and long respiratory events duration (200 and 275 seconds respectively) noted in polysomnography were reported at Ebn-e-Sina and Razavi hospita...

Hypertension, blood pressure variation, and resistant hypertension have close relations to sleep apnea, which lead to target organ damage, including the kidney. The complex relationships between sleep apnea and blood pressure cause their interactions with chronic kidney disease ambiguous. The aim of the study was to elucidate the separate and joint effects of sleep apnea, hypertension, and resi...

A randomized, controlled study of a mandibular advancement splint for obstructive sleep apnea. Efficacy of positive airway pressure and oral appliance in mild to moderate obstructive sleep apnea. advancement devices in 630 men and women with obstructive sleep apnea and snoring: tolerability and predictors of treatment success. Assessment of upper airway dynamics in awake sleep apnea patients wi...

Obstructive sleep apnea is increasingly recognized as an important contributor to cognitive impairment, metabolic derangements, and cardiovascular disease and mortality. Identifying the mechanisms by which this prevalent disorder influences health outcomes is now of utmost importance. As the prevalence of this disorder steadily increases, therapies are needed to prevent or reverse sleep apnea m...

Punjabi, Naresh M., and Vsevolod Y. Polotsky. Disorders of glucose metabolism in sleep apnea. J Appl Physiol 99: 1998–2007, 2005; doi:10.1152/ japplphysiol.00695.2005.—Sleep is a complex behavioral state that occupies onethird of the human life span. Although viewed as a passive condition, sleep is a highly active and dynamic process. The sleep-related decrease in muscle tone is associated with...