Every year over 1.5 million men develop prostate cancer and it is also a significant cause of mortality among men. There are multiple factors upregulating cancer, which includes mutation in the genetics, ethnicity or hereditary. Out 23 MMPs, there 4 MMPs mostly upregulated cancer. function by deteriorating several proteins present extracellular matrix. Catharanthus roseus medicinal plant has an...

IN THE sixteenth and early seventeenth centuries extravagant notions had been held of tobacco as the Herba Panacea, Heilkraut, and Herbe propre 'a tous maux. In the course of time these had waned and tobacco had come to be consumed more often for pleasure than for health, but about 1800 tobacco was still being used as a remedy for many ills. "Tobacco is narcotic, sedative, emetic, diuretic, cat...

Article history Received 11 June 2011 Revised 24 July 2011 Accepted 8 December 2011 Available online 30 April 2012 Rubia tinctorum L. (Rubiaceae) root is traditionally used in Morocco for treating the gastro-intestinal diseases. The aim of the present study was to assess the antispasmodic effects of the aqueous extract of this root plant (AR) on rodents.The effect of the AR on spontaneous contr...

Tribulus terrestris (family Zygophyllaceae), commonly referred to as Gokshur or Gokharu puncture vine, has long been used in both Indian and Chinese medicine systems treat various ailments. Its components contain a variety of chemicals that are important for healing, such flavonoids, flavonol glycosides, steroidal saponins, alkaloids. Contains diuretic, aphrodisiac, antiurolithic, immunomodulat...

BACKGROUND Morinda citrifolia (Noni) is an edible plant with wide range of medicinal uses. It occurs exclusively in tropical climate zone from India through Southeast Asia and Australia to Eastern Polynesia and Hawaii. The objective of this study was to explore the possible mode(s) of action for its antispasmodic, vasodilator and cardio-suppressant effects to rationalize its medicinal use in gu...

Pycnocycla caespitosa is an essential oil-containing plant naturally growing in southwest of Iran. The extract of this plant has been used as remedy in traditional medicine. Another species of Pycnocyla (P. spinosa) possessed antispasmodic activity. The pharmacological objective of this study was to look for relaxant effect of hydroalcoholic extract and essential oil of P. caespitosa on rat iso...

BACKGROUND Rubus fruticosus is used in tribal medicine as anthelmintic and an antispasmodic. In the current work, we investigated the anthelmintic and antispasmodic activities of crude methanol extract of fruits of R. fruticosus on scientific grounds. Acute toxicity and brine shrimp cytotoxicity activity of the extract were also performed. METHODS Acute toxicity study of crude methanol extrac...

BACKGROUND Viscum album has shown inhibitory effect on different smooth muscles but underlying mechanisms in gut and vascular smooth muscles are not well defined. Additionally, the plant has also importance in managing hyperactive gut and cardiovascular disorders. The current study was aimed to probe a pharmacological base of the smooth muscle relaxant effect of V. album in gut and vascular pre...