نتایج جستجو برای: antiplasmodial

تعداد نتایج: 1041  

Journal: :Molecules 2010
Guillaume Marti Véronique Eparvier Marc Litaudon Philippe Grellier Françoise Guéritte

Bioassay-guided fractionation of the ethyl acetate bark extract of Rheedia acuminata led to the isolation of the new compound 1,5,6-trihydroxy-3-methoxy-7-geranyl-xanthone, together with four known compounds. These compounds were tested in vitro for their antiplasmodial activity on a chloroquine-resistant strain of Plasmodium falciparum (FcB1) and for their cytotoxicity against the human diploi...

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Journal: :European journal of medicinal chemistry 2011
Matthias D'hooghe Sara Kenis Karel Vervisch Carmen Lategan Peter J Smith Kelly Chibale Norbert De Kimpe

A variety of 2-(aminomethyl)aziridines was prepared and converted into the corresponding 1,2,3-triaminopropanes through a novel, microwave-assisted and regioselective ring opening by diethylamine in acetonitrile. Antiplasmodial assays revealed antimalarial activity for 2-[(1,2,4-triazol-1-yl)methyl]aziridines and 2-(N,N-diethylaminomethyl)aziridines, as well as for the corresponding 1-(diethyla...

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2014
Vincent E. Rasamison L. Harinantenaina Rakotondraibe Carla Slebodnick Peggy J. Brodie Michel Ratsimbason Karen TenDyke Yongchun Shen Lucien M. Randrianjanaka David G. I. Kingston

The new triterpene turranoic acid (1) and the new N-containing nor-triterpene turraenine (2), along with triptocallic acid B (3) and esculentoic acid (4) were isolated from leaves of a Turraea sp. Compounds 1-3 showed weak to moderate in vitro antiplasmodial activity against the chloroquine-resistant Plasmodium falciparum strain FCM29. Compound 1 also displayed weak cytotoxic activity against t...

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Journal: :Antimicrobial agents and chemotherapy 2004
Hanne L Ziegler Harald S Hansen Dan Staerk Søren Brøgger Christensen Henry Hägerstrand Jerzy W Jaroszewski

The well-known antiparasitic compound licochalcone A is a potent membrane-active agent that transforms normal erythrocytes into echinocytes in parallel with the inhibition of growth of Plasmodium falciparum cultures, the in vitro antiplasmodial effect apparently being an indirect effect on the host cell. In vitro experiments with synchronous cultures demonstrate that inhibition of invasion is t...

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Journal: :Natural Product Communications 2019

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Journal: :Current Bioactive Compounds 2017

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Journal: :Asian Pacific Journal of Tropical Biomedicine 2012

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Journal: :Journal of Natural Products 2018

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Journal: :Asian Pacific Journal of Tropical Medicine 2012

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Journal: :Asian Journal of Medical Sciences 2014

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نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید

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