Antiphospholipid antibodies, including anticardiolipin antibodies, are frequently detected in sera from patients with systemic lupus erythematosus (1). Numerous reports have associated these autoantibodies with various venous and arterial thrombotic disorders, including cerebral infarction (2), deep venous thrombosis (3), thrombocytopenia (1), pulmonary embolism (4), and recurrent fetal loss wi...

A child with systemic onset juvenile chronic arthritis (JCA) who developed a bilateral femuropopliteal vein thrombosis after plaster immobilisation following a tibial fracture is described. When the thrombosis was diagnosed, antiphospholipid antibodies detected either as lupus anticoagulant and anticardiolipin antibodies were found. This suggests that short term prophylatic antithrombotic treat...

The clinical study of stroke is a recent occurrence. The clarion call awakening interest consisted of two reports that appeared during the years following World War II : the detailed description by Kubik and Adams [1) of the clinical and pathologic findings in patients with basilar artery occlusion, and C. Miller Fisher's monograph [2] directing attention to the signs and symptoms found in pati...

Many infections have been found to be associated with antiphospholipid antibodies (aPL), although a pathogenic role for these antibodies has not usually been obvious except in a few isolated cases. Two types of aPL have been referred to as "autoimmune" and "infectious" types. This distinction, however, has subsequently been found not to be absolute.