The present study demonstrates tissue-specific (hemolymph and fat body) and inter-voltine [bivoltine (BV) and trivoltine (TV)] differences in oxidatively damaged products, H2O2 content, and the relative level of antioxidant protection in the diapausing pupae of Antheraea mylitta. Results suggest that fat body (FB) of both the voltine groups has oxidative predominance, as evident from the high v...

Chronic obstructive pulmonary disease (COPD) is a common disorder that is related to smoking in susceptible individuals. The epidemiology is complex and includes both environmental and host factors. Early identification and intervention via smoking cessation and possibly the augmentation of antioxidant defenses in the lung offer hope to prevent and forestall premature morbidity and mortality fo...

Background Bronchopulmonary Dysplasia (BPD) is a multifactorial disease with a significant genetic component. Twin studies indicate that heritability of BPD is estimated at 53 to 79% [1]. Association studies have identifiedseveral potential candidate genes encoding components of innate immune and antioxidant defenses, mechanisms of vascular and lung remodeling, matrix remodeling proteins, surfa...

BACKGROUND Oxidative stress, as measured by 8-iso-prostaglandin F(2)(alpha) (8-iso-PGF(2)(alpha)), and depleted antioxidant defenses were shown in stable cystic fibrosis (CF) patients. The plasma fatty acid status of CF patients was linked to oxidative stress after respiratory exacerbations. OBJECTIVE We examined changes in plasma 8-iso-PGF(2)(alpha), antioxidant defenses, plasma fatty acid s...

Perinatal exposure to nicotine imbalances the redox status in newborns. This study investigated effect of Anethum graveolens (dill) extract on oxidative stress and tissue injury liver kidney mice newborns exposed perinatally. Pregnant received (0.25 mg/kg) gestational day 12 5 after birth and/or A. 1 15 birth. Newborn showed multiple histopathological alterations liver, including inflammatory c...

The frequency of Crohn disease shows a significant increase in the last century. Affected patients show a misbalance between production of free radicals and anti oxidant defenses. Thus, one of the increasingly accepted htypotheses to explain the origin of this disease, is the oxidative stress that occurs in the intestinal mucosa. Dietary factors including self administered vitamin and mineral s...