نتایج جستجو برای: antimalaria activities
تعداد نتایج: 377407 فیلتر نتایج به سال:
Aided by the Plasmodium falciparum genome project, recent discoveries regarding the molecular basis of malaria pathogenesis have led to a better understanding of the interactions between host and parasite. Although vaccines that prevent infection by malaria parasites remain only hopes for the future, there are now more immediate prospects for vaccines that protect against specific disease syndr...
BACKGROUND Mefloquine is a clinically important antimalaria drug, which is often not well tolerated. We critically reviewed 516 published case reports of mefloquine adverse effects, to clarify the phenomenology of the harms associated with mefloquine, and to make recommendations for safer prescribing. PRESENTATION We postulate that many of the adverse effects of mefloquine are a post-hepatic ...
Malaria parasitemia was assessed in 37 known sickle cell anemia patients attending the routine hematological clinic of the University of Benin Teaching Hospital, Benin-City, Edo State. Parasitemia was determined using the quantitative buffy coat analysis. The prevalence of malaria parasitemia among the population studied was 86.5%. There was no significant difference in the prevalence of parasi...
Drugs for Neglected Diseases initiative’s mission & business model Scope of diseases, unmet needs & activities covered by Drugs for Neglected Diseases initiative The Drugs for Neglected Diseases initiative (DNDi) is an international and nongovernmental not-for-profit organization committed to the development of novel and/or improved treatments for neglected diseases. The diseases chosen initi...
abstract governing was disorganized for years, when mongols attached to iran and it caused to clearing way for interference of mongols princes. dispatching of holaku to the west culminated in establishing iilkhanan government. holakus activities in destruction of abbaasis government and activities which shows his staying in iran, made force oulus juji to comparison against iilkhanis gover...
the present research study attempted to find out the extent to which two pre-task activities of “glossary of unknown vocabulary items” and “content related support” assisted efl language learners with their performance on listening comprehension questions across two different proficiency levels (low and high). data for this study were obtained from a total of 120 language learners, female and m...
abstract recent studies suggest that prelistening activities play an important role in the development of listening comprehension (e.g. long 1990;chiang and dunkel 1992; schmidt-rinehart 1994; jensen and hansen 1995; robinson et al., 1995; buck, 1995; foster and skehan,1996; teng 1996; robinson, 2001; chang and read 2006). in line with previous studies and to shed light on a new aspect of sche...
Purpose: To synthesize chloro-pyrazolines (A–D), determine their antimalarial activity against Plasmodium falciparum strain 3D7 in vitro, and understand the interaction between falcipain-2 active sites synthesized compounds by molecular docking simulation.Methods: Chloro-pyrazolines (A–D) were via cyclo-condensation of 4-chloro chalcone derivatives using several types hydrazines, i.e., formylhy...
Development of new antimalaria strategies and particularly vaccines, needs an in-depth understanding of the relationships between transmission, infection, immunity, morbidity and mortality. The intensive and longitudinal collection of entomological, parasitological and clinical data from the Senegalese populations of Dielmo (250-300 inhabitants), exposed to a perennial and intense transmission ...
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