Coumarin derivatives have shown different biological activities, such as antifungal, antibacterial antiinflammatory, and antioxidant besides antibiotic resistance modulating effects, anti-HIV, hepatoprotective, antitumor effect. So, new coumarin (hydrazones an amide) were synthesized through multisteps reactions. All the target compounds characterized by FT-IR spectroscopy, 1HNMR analysis. The ...

Atherosclerosis, the underlying cause of heart attack and stroke, appears to be an inflammatory disease driven by retention of modified lipoproteins in the artery wall.1 Markers of inflammation, such as high sensitivity C-reactive protein, are independent predictors of cardiovascular (CV) events.2 If atherosclerosis truly is an inflammatory disease, then shouldn’t we be able to identify antiinf...