The present study aimed to investigate the phytochemical profile of leaf methanol extracts of fourteen Smallanthus sonchifolius (yacon) landraces and their antioxidant, anticholinesterase and antidiabetic activities that could lead to the finding of more effective agents for the treatment and management of Alzheimer's disease and diabetes. For this purpose, antioxidant activity was assessed usi...

In this study, 11 lactic acid bacteria (LAB) strains were screened for potential new probiotics using in vitro methods, including acid and bile salt tolerance, adhesion, antioxidative and a-glucosidase inhibitory activity. The results indicated that Lactobacillus casei 2W and Lactobacillus rhamnosus Z7 showed better potential probiotic properties and a-glucosidase inhibitory activity in vitro. ...

Plants have been historically used for diabetes treatment and related anti-inflammatory activity throughout the world; few of them have been validated by scientific criteria. Recently, a large diversity of animal models has been developed for better understanding the pathogenesis of diabetes mellitus and its underlying inflammatory mechanism and new drugs have been introduced in the market to t...

Medicinal plants have curative properties due to the presence of various complex chemical compositions, which are found as secondary plant metabolites in one or more parts of the plant. The aim of this study was to compute the antidiabetic activity of Holarrhena antidysenterica   seeds extract in streptozotocin-induced diabetic rats. The experimental protocol designed as animals were divided i...

objective(s):ethnopharmacological field surveys demonstrated that many plants, such as gentiana olivieri, helichrysum graveolens, helichrysum plicatum ssp. plicatum, juniperus oxycedrus ssp. oxycedrus, juniperus  communis var. saxatilis, viscum album (ssp. album, ssp. austriacum), are used as traditional medicine for diabetes in different regions of anatolia. the present study was designed to e...

Diabetes is a group of metabolic diseases characterized by hyperglycemia. Insulin resistance (IR) and insufficient insulin secretion are important pathophysiological basis significant characteristics diabetes. At present, animal still the main model for investigation Antidiabetic activity bioactive substances, however, in vivo models always has problems long experimental cycle, complicated expe...

One of the biological wealth that grows in Papua is Alstonia scholaris, known by Maybrat tribe as swe plant and used a traditional medicine for antidiabetic. The Swe tree contains lot white sap tastes very bitter. There also bitter taste roots, bark, leaves so it thought to contain bioactive compounds alkaloids which have potential This study aims extract determine antidiabetic activity inhibit...

Thiazolidinediones are a class of well-established antidiabetic drugs, also named as glitazones. Thiazolidinedione structure has been an important structural domain of research, involving design and development of new drugs for the treatment of type 2 diabetes. Extensive research on the mechanism of action and the structural requirements has revealed that the intended antidiabetic activity in t...

Recently, the interest in possible health benefits of medicinal plants as antioxidant and hypoglycaemic supplements has increased, due to their phytochemical compounds exhibiting potent antioxidant properties. The aim of this study was to assess the in vivo antioxidant activity and antidiabetic potential of a tincture of Syringae vulgaris flos f. violácea (SV), properties less investigated for ...