The Mhlathuze River has become a major reservoir for antibiotic-resistant microbes and a wide pool of antibiotic resistant genes with the environmental isolates exists in this water system. The ability of commensal organisms to carry resistant genes of clinical importance and their ability to transfer such genes to other bacteria are of greater concern than phenotypic measurements. Forty-three ...

Glycopeptide antibiotics containing a hydrophobic substituent display the best activity against vancomycin-resistant enterococci, and they have been assumed to be poor inducers of the resistance system. Using a panel of 26 glycopeptide derivatives and the model resistance system in Streptomyces coelicolor, we confirmed this hypothesis at the level of transcription. Identification of the structu...

Background: The spread of resistant bacteria has caused serious concern worldwide. multidrug-resistant (MDR) and extensive drug-resistant (XDR) limits the choice antibiotics, making available antibiotics less effective. Objectives: This study aimed to investigate resistance patterns seven global threatening organisms announced by Centers for Disease Control Prevention (CDC) one year in Iran, ca...

• Antibiotic manufacture, as well as its use, contributes to antibiotic residues in the environment, which leads to development of resistant bacteria • In South East Asia, wastewater containing antibiotics is often directly released into the environment without sufficient treatment • Research must focus on developing efficient, affordable, small scale treatment plants to eliminate antibiotic re...

conclusions the current study results showed that silver nanoparticles produced by plantago ovata seed extract had an antibacterial effect on staphylococcus aureus which was resistant against cefixime, trimethoprim-sulfamethoxazole and penicillin. results the silver nanoparticles revealed gaussian distributions with the average diameter of 13 nm with some deviations, and results showed that the...

There is concern that antibiotic resistance can potentially be transferred from animals to humans through the food chain. The relationship between specific antibiotic resistant bacteria and the genes they carry remains to be described. Few details are known about the ecology of antibiotic resistant genes and bacteria in food production systems, or how antibiotic resistance genes in food animals...

objectives in this study, we explored a physical method of converting drug-resistant bacteria to drug-sensitive ones. materials and methods this is an in vitro case-control study, performed at the ionizing and non-ionizing radiation protection research center (inirprc), shiraz university of medical sciences (sums), shiraz, iran in 2014. all experiments were carried out using gram-negative bacte...

objectives the study was carried out in a tertiary care center in tehran, iran to identify the frequency of hospital acquired methicillin resistant staphylococcus aureus (ha-mrsa ) colonization and its antibiotic susceptibility pattern and molecular characteristics. patients and methods this point-prevalence study was performed on 631 children who were admitted for at least 48 hours in differen...

Antibiotic-resistant bacteria have posed a grave threat to public health by causing a number of nosocomial infections in hospitals. Mathematical models have been used to study transmission dynamics of antibiotic-resistant bacteria within a hospital and the measures to control antibiotic resistance in nosocomial pathogens. Studies presented in Lipstich et al. (Proc Natl Acad Sci 97(4):1938-1943,...

Abstract Antibiotic resistance in soil environment has eminently been compared and studied between agricultural pristine soils, the role of concentrated animal feeding operations markedly recognized as one major sources antibiotic resistance. This study described tetracycline small-scale farms pursuit presenting its possible contribution to persistence environment. Results would render addition...