نتایج جستجو برای: anti proliferative

تعداد نتایج: 388579  

جعفری انارکولی, ایرج, عبدانی پور, علیرضا, قربانلو, مهرداد, نجات بخش, رضا, نوریان, امبر, نیک فر, علی,

Background and Objective: Nowadays, extensive research is carried out on the effect of plant extracts on variety of disorders. In this study, the effect of hydroethanolic extract of Lavandula officinalis on proliferation of neural stem cells as well as its anti-apoptotic properties was assessed. Materials and Methods: Neural stem cells were isolated from hippocampus of neonatal rat brain. To...

2012
Daniele Rossi Stefano Pianta Marta Magatti Peter Sedlmayr Ornella Parolini

We previously demonstrated that cells isolated from the mesenchymal region of the human amniotic membrane (human amniotic mesenchymal tissue cells, hAMTC) possess immunoregulatory roles, such as inhibition of lymphocyte proliferation and cytokine production, and suppression of generation and maturation of monocyte-derived dendritic cells, as reported for MSC from other sources. The precise fact...

Journal: :The Journal of clinical investigation 1997
D Bokemeyer K E Guglielmi A McGinty A Sorokin E A Lianos M J Dunn

Multiple extracellular mitogens are involved in the pathogenesis of proliferative forms of glomerulonephritis (GN). In vitro studies demonstrate the pivotal role of extracellular signal-regulated kinase (ERK) in the regulation of cellular proliferation in response to extracellular mitogens. In this study, we examined whether this kinase, as a convergence point of mitogenic stimuli, is activated...

Journal: :Journal of immunology 1999
A Mathew I Kurane S Green D W Vaughn S Kalayanarooj S Suntayakorn F A Ennis A L Rothman

Decreased proliferative responses to mitogens and recall Ags have been observed in PBMC obtained during several acute human viral infections. To determine whether cell-mediated responses are altered during acute dengue infection, we examined the proliferative responses of PBMC from children enrolled in a prospective study of dengue infections in Thailand. All responses of PBMC during acute illn...

Journal: :Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 1998
R Corrêa-Oliveira L C Malaquias P L Falcão I R Viana L M Bahia-Oliveira A M Silveira L A Fraga A Prata R L Coffman J R Lambertucci J R Cunha-Melo O A Martins-Filho R A Wilson G Gazzinelli

The role of different cytokines in the peripheral blood mononuclear cell (PBMC) proliferative response and in in vitro granuloma formation was evaluated in a cross-sectional study with patients with the different clinical forms and phases of Schistosoma mansoni infection, as well as a group of individuals "naturally" resistant to infection named normal endemic (NE). The blockage of IL-4 and IL-...

Journal: :iranian journal of basic medical sciences 0
hojjat sadeghi-aliabadi department of biotechnology, faculty of pharmacy, isfahan university of medical sciences, isfahan, iran fatemeh mohammadi department of biotechnology, faculty of pharmacy, isfahan university of medical sciences, isfahan, iran hossain fazeli department of microbiology, medical school, isfahan university of medical sciences, isfahan, iran maryam mirlohi food security research center, school of nutrition and food science, isfahan university of medical sciences, isfahan, iran

objective(s): several beneficial effects have been attributed to the probiotic lactic acid bacteria. it was determined that lactobacilli can exert antiproliferative effects on the various cancer cell lines including colon cancer. effects of lactic acid bacteria on colon cancer may vary from strain to strain and there is a need to find the new probiotic strains with tumor suppressing properties ...

Journal: :research in pharmaceutical sciences 0

artemisia is an important genus of iranian flora whose potent anti-proliferative effect has been demonstrated previously on human cancerous cell lines. in the current study, further fractionation was carried out on the petroleum ether extract of a. aucheri and their cytotoxic effects were evaluated on three human cancer cell lines. cell viability was determined by 3-(4,5-dimethylthiazol-2yl)-2,...

Journal: :research in pharmaceutical sciences 0
fatemeh haji abbas tabrizi saeed irian amir amanzadeh fatemeh heidarnejad hoda gudarzi mona salimi

plant-derived natural products are known to have cancer chemo-preventive and chemo-therapeutic properties. plant extracts or their active constituents are used as folk medicine in traditional therapies by 80% of the world population. the aim of the present study was to determine the anti-proliferative potential of fumaria vaillantii extracts on three different cancer cell lines including malign...

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