methanolic extract of solanum trilobatum linn. (mest) belonging to the family of solanacea was evaluated by hot plate and acetic acid induced writhing methods to assess its analgesic activity. the extract was also evaluated for its anti-inflammatory activity by subjecting into carrageenan, and cotton pellet induced granuloma tests for its effect on acute and chronic phase inflammation models in...

the chemical composition of the essential oils of flower at the pre-flowering, full-flowering and post-flowering stage of a. annua was analyzed by gc and gc/ms and sixty-two components were identified. the main compounds in the pre-flowering oil were β-myrcene (37.71%), 1, 8-cineole (16.11%) and camphor (14.97%). the full-flowering oil contained predominantly caryophyllene (19.4%), germacrene d...

Background: Bacillus clausii is being studied as a probiotic candidate. There insufficient information on the antimicrobial and anticancer effects of B. clausii. Objectives: The present investigation was designed to evaluate anti-bacterial, anti-adenoviral, apoptosis-inducing activity cell-free supernatant (CFS). Methods: First, collected after culture for 24 h. Then, its anti-bacterial impact ...

Background: Anti-microbial resistance has become a major problem in clinical practice making it necessary to search for newer molecules. Acalypha wilkesiana, is herb commonly used traditionally in Nigeria treat gastrointestinal disorders, wounds and skin infections like impetigo. Objectives: To determine the in-vitro anti-bacterial activity of crude extracts 2 cultivars of Acalyp...

The increasing anti-bacterial drug resistance is one of the biggest challenges facing doctors around globe, so finding alternative treatments ideal options to overcome this problem. cruciferous family wealthiest plants worldwide because it contains most important secondary metabolites, glucosinolates, known for their anti-microbial properties. present study aimed evaluate effect glucosinolates ...

Thiosemicarbazides are potent intermediates for the synthesis of pharmaceutical and bioactive materials and thus, they are used extensively in the field of medicinal chemistry. The imine bond (-N=CH-) in these compounds are useful in organic synthesis, in particular for the preparation of heterocycles and non-natural β-aminoacids.In this paper the synthesis of some new thiosemicarbazide derivat...

Zoonotic cutaneous leishmaniasis caused by Leishmania major is a most common type of vector-borne disease in Iran. The pentavalent antimonial drugs have been used in the treatment of cutaneous leishmaniasis for a long time, but drug resistance and some of serious side effects have been reported. Thus, discovery and development of new therapeutic candidates are needed. The CM11 peptide ...

Madhuca longifolia commonly known as Mahua belonging to family Sapotaceae, is an Indian tropical tree, for its sweet flowers which are edible and used by tribals medicinal purpose. The pharmacological activity of the anti- inflammatory, anti-bacterial, anti-oxidant, analgesic, anti-pyretic wound healing properties has no side effect even after consumption larger doses. prevalence throat infecti...

The present work deals with the synthesis of some novel azo derivatives of dihydropyrimidinones. The structures of newly synthesized compounds were established on the basis of their FTIR, 1H NMR, Mass spectrometry and elemental analysis data results. The synthesized agents were assessed for their in vivo anti-inflammatory activity on the Wistar albino rats. The compounds were also screened for ...