background: although helicobacter pylori and non-steroidal anti-inflammatory drugs (nsaids) are the main causes of peptic ulcers disease (pud), recently the prevalence of idiopathic peptic ulcer (ipu) is increasing in most parts of the world. the aim of this study was to assess the prevalence of ipu in kerman, the center of largest province in south-east iran. methods : we included 215 patients...

NEW DRUGS Fusion Inhibitor for HIV The Food and Drug Administration (FDA) has announced the accelerated approval of enfuvir tide (FuzeonTM, Roche) for use with other anti-HIV medications in adults and children ages six years and older with advanced human immunodeficiency virus (HIV) infection. Enfuvirtide is the first in a new class of medications called fusion inhibitors, which interfere with ...

Epilepsy represents the most common serious neurological disorder, with a prevalence of 0.4 - 1%. Approximately 30% of patients are resistant to currently available drugs. New anti-epileptic drugs are needed to treat refractory epilepsy, improve upon current therapies, improve the prognosis of epilepsy and to prevent the epileptogenic process. Designing compounds with specific physiological tar...

This review of studies on anti-anginal agents and their use in the anginal syndrome shows nitroglycerin to be unsurpassed in clinical effectiveness. It has a rapid onset of action. Its duration of action is relatively short but the need for a more prolonged effect has not been demonstrated. Most anginal attacks subside upon resting and the requirement for relief is immediate rather than prolong...

Non-steroidal anti-inflammatory drugs (NSAIDs) are usually defined as those agents that inhibit one or more reactions involved in the production of prostaglandins and thromboxanes, important mediators of the inflammatory process in many organs and tissues. They find use in horses in the supportive treatment of a variety of systemic states and painful musculoskeletal or soft tissue conditions. T...

Background: Toxoplasma gondii (T. gondii) is an intracellular parasite mainly found in the central nervous system CNS, however, it can persist in multiple tissues in the body. Moreover, T. gondii is the commonest protozoans causing infections among individuals with acquired immunodeficiency syndrome (AIDS). Thus, the aim of this study was to investigate the frequency of T. gondii infection amon...

NEED AND PURPOSE OF REVIEW A number of newer anti-epileptic drugs have been developed in the last few years to improve the treatment outcomes in epilepsy. In this review, we discuss the use of newer anti-epileptic drugs in children. METHODS USED FOR LOCATING, SELECTING, EXTRACTING AND SYNTHESIZING DATA MEDLINE search (1966-2013) was performed using terms newer anti-epileptic drugs, Oxcarbazep...

Diabetes mellitus affects up to 6% of the UK population, although it is estimated that around half of these individuals remain undiagnosed. It occurs equally in both sexes but varies with age and race. The ethnic group at highest risk is the Pima Indians in North America with a 50% prevalence of diabetes. Other high-risk groups include the Afro-Caribbean and Asian populations, who are at four t...

anti-inflammatory activity has been reported for a few of antidepressant drugs and in contrary sertraline has potentiated inflammation. in this study, anti-inflammatory effect of a collection of antidepressant drugs belonging to different classes was evaluated to help a rational selection of these drugs in disease conditions such as association of depression or anxiety with inflammatory disease...