We propose a scheme for laser cooling of negatively charged molecules. We briefly summarize the requirements for such laser cooling and we identify a number of potential candidates. A detailed computation study with C_{2}^{-}, the most studied molecular anion, is carried out. Simulations of 3D laser cooling in a gas phase show that this molecule could be cooled down to below 1 mK in only a few ...

The ideas fundamental to the design of cation complexing host molecules can also be applied in the construction of molecular hosts for anions. Following the basic concept the macrotricyclic ammonium hosts la and j& were prepared. They were shown to bind anions by encapsulation into their molecular cavities in aqueous solution. This inclusion process causes guest discrimination according to inte...

Many biosensors have been developed to detect Hg(2+) using thymine-rich DNA. While sensor response to various cations is often studied to demonstrate selectivity, the effect of anions has been largely overlooked. Anions may compete with DNA for metal binding and thus produce a false negative result. Anions cannot be added alone; the cation part of a salt may cause DNA compaction and other effec...

The role of cations in excitation energy distribution between the two photosystems of photosynthesis is well established. This paper provides evidence, for the first time, for an important role of anions in the regulation of distribution of absorbed light energy between the two photosystems. Inorganic anions caused redistribution of energy more in favour of photosystem I, as judged from measure...

Acid-sensing ion channels (ASICs) are sodium channels gated by extracellular protons. ASIC1a channels possess intersubunit Cl(-)-binding sites in the extracellular domain, which are highly conserved between ASIC subunits. We previously found that anions modulate ASIC1a gating via these sites. Here we investigated the effect of anion substitution on native ASICs in rat sensory neurons and hetero...

A series of fluorescent carbazolylurea base anion receptors have been synthesised that show a high affinity for oxo-anions (particularly bicarbonate and acetate). The fluorescence of dicarbazolylurea (1) is quenched upon addition of benzoate anions in DMSO-0.5% water.

A distinctive feature of the voltage-dependent chloride channels ClC-0 (the Torpedo electroplaque chloride channel) and ClC-1 (the major skeletal muscle chloride channel) is that chloride acts as a ligand to its own channel, regulating channel opening and so controlling the permeation of its own species. We have now studied the permeation of a number of foreign anions through ClC-1 using voltag...

The ferrocene-pyrylium dyad behaves as a selective redox and colorimetric chemodosimeter for CN(-) and HS(-) anions, exhibiting a clear perturbation in the redox potential of the ferrocene unit and in the absorption band, in the presence of these anions.

The sphingolipid, ceramide 1, facilitates transport of Cl(-) and HCO(3)(-) anions across lipid bilayers under conditions where large transmembrane pores are not formed. Ceramide's 1,3-diol unit is essential for both binding and transporting these anions.