نتایج جستجو برای: angle glaucoma poag

تعداد نتایج: 146295  

2013
Emmanuel S. Buys Yu-Chieh Ko Clemens Alt Sarah R. Hayton Alexander Jones Laurel T. Tainsh Ruiyi Ren Andrea Giani Maeva Clerté Emma Abernathy Robert E. T. Tainsh Dong-Jin Oh Rajeev Malhotra Pankaj Arora Nadine de Waard Binglan Yu Raphael Turcotte Daniel Nathan Marielle Scherrer-Crosbie Stephanie J. Loomis Jae H. Kang Charles P. Lin Haiyan Gong Douglas J. Rhee Peter Brouckaert Janey L. Wiggs Meredith S. Gregory Louis R. Pasquale Kenneth D. Bloch Bruce R. Ksander

Primary open angle glaucoma (POAG) is a leading cause of blindness worldwide. The molecular signaling involved in the pathogenesis of POAG remains unknown. Here, we report that mice lacking the α1 subunit of the nitric oxide receptor soluble guanylate cyclase represent a novel and translatable animal model of POAG, characterized by thinning of the retinal nerve fiber layer and loss of optic ner...

2017
Zhenxian Hu Chenliang He

The aim of this meta-analysis was to evaluate the association between cyclin-dependent kinase Inhibitor-2B (CDKN2B) gene rs1063192 polymorphism and glaucoma risk. We searched the databases of PubMed, and Embase. Pooled odds ratios (ORs) and 95% confidence intervals (CIs) were calculated by using fixed-effect or random-effect models. A total of 14 case-control studies involving 11,316 cases and ...

Journal: :American journal of ophthalmology 2009
Fotis Topouzis Alon Harris M Roy Wilson Archimidis Koskosas Panayiota Founti Fei Yu Eleftherios Anastasopoulos Theofanis Pappas Anne L Coleman

PURPOSE To compare the clinical characteristics of primary open-angle glaucoma (POAG) and pseudoexfoliative glaucoma (PEXG) identified in the Thessaloniki Eye Study and to evaluate the proportion of subjects with and without pseudoexfoliation (PEX) who have glaucoma by screening intraocular pressure (IOP). DESIGN Cross-sectional, population-based study. METHODS Randomly selected subjects > ...

Journal: :Archives of ophthalmology 2002
Wallace L M Alward Young H Kwon Cheryl L Khanna A Tim Johnson Sohan S Hayreh M Bridget Zimmerman Joanna Narkiewicz Jeaneen L Andorf Paula A Moore John H Fingert Val C Sheffield Edwin M Stone

OBJECTIVE To determine the prevalence and associated phenotype of myocilin (MYOC) coding sequence variations and a specific promoter polymorphism (MYOC.mt1) in patients with glaucoma and glaucoma suspects. METHODS A consecutive, unselected series of 779 patients (652 with open-angle glaucoma and 127 glaucoma suspects) were recruited from a university medical center and clinically characterize...

Journal: :journal of current ophthalmology 0
حمید فشارکی hamid fesharaki حسن رزمجو hassan razmjoo محمد قریشی mohammad ghoreishi حسین عطارزاده hossein attarzadeh اکرم ریسمانچیان akram rismanchian علیرضا پیمان alireza peyman

purpose : there are controversial reports regarding the long-term intraocular pressure (iop) lowering effect of non-penetrating glaucoma surgery (npgs). the reported complete success rates from studies in different populations around the world are 13% to 77%. this prospective study was aimed to evaluate the iop lowering effect of deep sclerectomy with mitomycin c (dsmmc) in a group of iranian p...

Journal: :International journal of medical science and clinical research studies 2022

Glaucoma is the leading cause of irreversible blindness worldwide and it important to assess impact timely diagnosis treatment on this disease due complications can bring patients. It an insidious pathology sometimes usually detected spontaneously in ordinary consultations. The most frequent type glaucoma primary open-angle (POAG), being second according WHO. Making known providing information ...

2014
Jaromir T. Wasyluk Anita Piekarniak-Woźniak Iwona Grabska-Liberek

INTRODUCTION Selective laser trabeculoplasty (SLT) is applied to reduce intraocular pressure in primary open angle glaucoma therapy. It selectively subjects trabecular pigmented cells to a pulsed, frequency-doubled Nd:YAG laser. The biostimulatory effect on trabecular macrophages was also postulated even in low-pigmented angles. The aim of the study was to assess the hypotensive effectiveness o...

Journal: :Japanese journal of ophthalmology 1999
T Yamamoto M Maeda A Sawada K Sugiyama T Taniguchi Y Kitazawa Z Oyama N Ichihashi H Takagi Y Kitajima

PURPOSE To investigate the prevalence of normal-tension glaucoma (NTG) and primary open-angle glaucoma (POAG) in patients with collagen diseases and determine whether an immunocompromised condition is present in a subset of glaucoma patients. METHODS Three glaucoma specialists prospectively examined patients with collagen diseases. The diagnostic process included applanation tonometry, slit-l...

Journal: : 2023

Introduction . Glaucoma is a socially significant disease. With the advent of new technologies it has become possible to diagnose this disease at an earlier stage. The aim investigation was reveal relationships between biomechanical parameters optic nerve disc (OND) in patients with primary open-angle glaucoma (POAG) against background achieving "target" intraocular pressure (IOP). Material and...

Journal: :The British journal of ophthalmology 2003
G Gazzard P J Foster J G Devereux F Oen P Chew P T Khaw S Seah

AIM To compare the correlation between visual field loss and the pretreatment intraocular pressure (IOP) in primary angle closure glaucoma (PACG) and primary open angle glaucoma (POAG). METHODS In a cross sectional observational study of 74 patients (43 PACG, 31 POAG), pretreatment IOP was measured at presentation, before treatment was initiated. The severity of visual field loss was assessed...

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