نتایج جستجو برای: angiotensinogen m235t polymorphism
تعداد نتایج: 109322 فیلتر نتایج به سال:
BACKGROUND Essential hypertension is a common, polygenic, complex disorder resulting from interaction of several genes with each other and with environmental factors such as obesity, dietary salt intake, and alcohol consumption. Since the underlying genetic pathways remain elusive, currently most studies focus on the genes coding for proteins that regulate blood pressure as their physiological ...
With the human genome project nearing completion and with the increasing availability of genotyping technology, there is considerable interest in identifying genes that contribute to hypertension and to physiological determinants of hypertension. In a number of relatively rare hypertensive disorders, specific genetic polymorphisms resulting in elevated arterial pressure have recently been descr...
CONTEXT The renin-angiotensin system (RAS) interacts with the autonomic nervous system (ANS) in the regulation of blood pressure and cardiovascular function. Several genetic polymorphisms in the RAS have been identified and have been implicated as a cause of hypertension and cardiovascular disease. OBJECTIVE The aim of the present study was to evaluate the relation between genetic polymorphis...
In this study of 10 690 individuals, associations with elevated blood pressure, ischemic heart disease, and ischemic cerebrovascular disease were determined for two noncoding [A(-20)C, G(-6)A] and two coding (T174M, M235T) single nucleotide polymorphisms, analyzed alone and in combination (haplotypes). Participants from the general population with (n=4950) and without (n=4234) elevated blood pr...
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