نتایج جستجو برای: angiotensin ii receptor

تعداد نتایج: 1146049  

Journal: :Circulation research 1999
D E Dostal K M Baker

Angiotensin II, the effector peptide of the renin-angiotensin system, regulates cellular growth in response to developmental, physiological, and pathological processes. The identification of renin-angiotensin system components and angiotensin II receptors in cardiac tissue suggests the existence of an autocrine/paracrine system that has effects independent of angiotensin II derived from the cir...

2013
Ju-Young Moon

The activation of renin-angiotensin-aldosterine system(RAAS) is one of the main pathogenesis of hypertension. All the components of RAAS are present in the kidneys at higher concentrations compared to plasma levels, and intrarenal formation of angiotensin II (Ang II) is independent of the systemic RAAS. There are some unique features in intrarenal RAAS compared to systemic RAAS. Unlike JG cells...

Journal: :Journal of hypertension and management 2023

Bilateral renal artery stenosis (RAS) causing recurrent hypertensive emergency and pulmonary oedema is difficult to manage. Use of angiotensin converting enzyme inhibitors (ACEi) II receptor blockers (ARB) usually contraindicated. We present a systematic review literature case vignette which highlights the useful properties this mineralocorticoid antagonists (MRAs) in scenario.

Journal: :Hypertension 2015
Wenguang Feng Phillip Chumley Minolfa C Prieto Kayoko Miyada Dale M Seth Huma Fatima Ping Hua Gabriel Rezonzew Paul W Sanders Edgar A Jaimes

Transcription factor E26 transformation-specific sequence-1 (ETS-1) is a transcription factor that regulates the expression of a variety of genes, including growth factors, chemokines, and adhesion molecules. We recently demonstrated that angiotensin II increases the glomerular expression of ETS-1 and that blockade of ETS-1 ameliorates the profibrotic and proinflammatory effects of angiotensin ...

1999
David E. Dostal Kenneth M. Baker

Angiotensin II, the effector peptide of the renin-angiotensin system, regulates cellular growth in response to developmental, physiological, and pathological processes. The identification of renin-angiotensin system components and angiotensin II receptors in cardiac tissue suggests the existence of an autocrine/paracrine system that has effects independent of angiotensin II derived from the cir...

2016
Kana Tsukuda Masaki Mogi Jun Iwanami Harumi Kanno Hirotomo Nakaoka Xiao-Li Wang Hui-Yu Bai Bao-Shuai Shan Masayoshi Kukida Akinori Higaki Toshifumi Yamauchi Li-Juan Min Masatsugu Horiuchi

Browning of white adipose tissue (WAT) has been highlighted as a new possible therapeutic target for obesity, diabetes and lipid metabolic disorders, because WAT browning could increase energy expenditure and reduce adiposity. The new clusters of adipocytes that emerge with WAT browning have been named 'beige' or 'brite' adipocytes. Recent reports have indicated that the renin-angiotensin syste...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2013
Mariana Kiomy Osako Hironori Nakagami Munehisa Shimamura Hiroshi Koriyama Futoshi Nakagami Hideo Shimizu Takashi Miyake Masao Yoshizumi Hiromi Rakugi Ryuichi Morishita

OBJECTIVE Vascular calcification is accelerated by hypertension and also contributes to hypertension; however, it is an enigma why hypertension and vascular calcification are a vicious spiral. The present study elucidates the cross-talk between renin-angiotensin II system and receptor activator of nuclear factor-κB ligand (RANKL) system in vascular calcification. APPROACH AND RESULTS Angioten...

Journal: :American Journal of Health-System Pharmacy 2000

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