نتایج جستجو برای: angiostatin

تعداد نتایج: 401  

Journal: :Proceedings of the National Academy of Sciences 1999

Journal: :Cancer research 2001
K Camphausen M A Moses W D Beecken M K Khan J Folkman M S O'Reilly

The surgical removal of a primary tumor can result in the rapid growth of metastases. The production of angiogenesis inhibitors by the primary tumor is one mechanism for the inhibition of metastatic tumor growth. The effect of curative radiotherapy to a primary tumor known to make an inhibitor of angiogenesis and the effects on distant metastases has not been studied. We here show that the erad...

Journal: :Cancer research 2003
Ruud P M Dings Yumi Yokoyama Sundaram Ramakrishnan Arjan W Griffioen Kevin H Mayo

Recently, we demonstrated that the designed peptide anginex displays potent antiangiogenic activity. The aim of the present study was to investigate anginex treatment as a single-agent therapy and to test its ability to improve conventional chemotherapy and antiangiogenesis therapy. In a human ovarian carcinoma mouse model, anginex inhibited tumor growth by 70%. When anginex was combined with a...

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