Since its introduction, percutaneous coronary intervention (PCI) has been limited by 2 major factors: restenosis and vessel closure attributable to thrombosis. The use of coronary stents has had a marked beneficial impact on rates of restenosis.1,2 However, the vessel trauma that occurs during PCI induces platelet activation, and all currently available coronary stents are made of metal and are...

AIMS We investigated whether routine T-stenting reduces restenosis of the side branch as compared with provisional T-stenting in patients with de novo coronary bifurcation lesions. METHODS AND RESULTS Our randomized study assigned 101 patients with a coronary bifurcation lesion to routine T-stenting with sirolimus-eluting stents (SES) in both branches and 101 patients to provisional T-stentin...

Background. Prevention of abrupt vessel closure after percutaneous transluminal coronary angioplasty (PTCA) represents one of the current indications for intracoronary stent implantation. After the procedure, the stented segment undergoes luminal changes that may lead to late restenosis. This study was undertaken to assess the time course of luminal changes during the first year after emergency...

Among 268 patients undergoing percutaneous transluminal coronary angioplasty between February 1980 and January 1983, a total of 21 patients had variant angina, documented before angioplasty in 14 and after angioplasty in 7. Before angioplasty, all 21 patients had rest angina and 17 also had effort angina; single vessel coronary artery disease with 60 to 95% stenosis was present in all patients ...

In the past few years, we have witnessed a dramatic proliferation in the use of stents as a treatment for symptomatic coronary artery disease. Stents now account for over 60% of catheter-based coronary interventions in the U.S. In 1998, 500,000 patients were treated with stents (1). Several factors have contributed to this explosive increase: the reassuring early results achieved with stenting,...

Of 552 patients undergoing percutaneous transluminal coronary angioplasty 102 had coronary artery spasm superimposed on atherosclerotic narrowing. Coronary angioplasty was successful in 97 (95%). The patients were discharged on a regimen of nifedipine (40-60 mg/day). Seventy six patients were symptom free 6-8 months after the procedure. Restenosis was detected in 35% of patients. Coronary arter...

BACKGROUND Since the introduction of stents in 1994, improved clinical results have boosted the development of coronary angioplasty in Chile. Drug eluting stents, that have a reduced rate of restenosis, are being increasingly used. AIM To assess the acute and long-term results of bare metal stent implantation. PATIENTS AND METHODS Acute and long-term clinical, procedural and angiographic re...

Thirty-five years after Charles Dotter first proposed the concept of an endovascular prosthesis, stenting has now emerged as the dominant technology for percutaneous coronary revascularization (1). In many laboratories, more than half of all patients undergoing catheter-based intervention receive at least one stent, and in some the use of stents approaches 80%. Although originally approved as t...

coronary artery disease has dramatically altered the practice of coronary artery bypass grafting surgery. New complications caused by percutaneous coronary interventions (PCI) with the implantation of stents has emerged and affected the result when surgery is subsequently required. The stent was initially utilized for the treatment of complications associated with percutaneous coronary angiopla...

OBJECTIVES Initial and late results after implantation of Freedom stents, a balloon expandable stainless steel coil stents were evaluated. METHODS From Jun. 1996 to Nov. 1997, we implanted 123 Freedom stents in 122 lesions in 117 patients and performed follow-up coronary angiograms at 7.0 +/- 3.6 months after stents placement. Clinical courses after stenting and follow-up coronary angiographi...