METHODS: We enrolled 12 consecutive male patients affected with androgenic alopecia at our private practice. Patients were excluded if they were or had been under treatment with oral finasteride or laser or injectable treatment for hair regrowth in the previous 6 months. Patients under topical minoxidil (2% or 5%) were given a wash out period of 60 days. Each patient was given a single injectio...

OBJECTIVE To evaluate the incidence of benign prostatic hyperplasia (BPH) and metabolic syndrome in patients with androgenetic alopecia (AGA) in comparison with those with no AGA, as several previous studies have reported inconsistent results of an association between metabolic syndrome and BPH with AGA. PATIENTS SUBJECTS AND METHODS This cross-sectional study included 400 participants, divid...

The aim of the research. To expand knowledge about immunohistochemical changes in female patients with androgenetic alopecia (AGA) focusing on non-androgenic co-factors pathogenesis disease, as this may serve a basis for improving therapeutic regimens.
 Materials and methods. Scalp biopsies were examined by method. study included two groups: main group 30 aged 22 to 40 years, average age 3...

The Gulf Journal of Dermatology and Venereology INTRODUCTION Androgenetic alopecia (AGA) is a hereditary and androgen-dependent progressive thinning of the scalp hair in a defined pattern. It is a common dermatological disorder affecting more men and occasionally women, with significant negative impact on their social and psychological well being. AGA commonly begins by 20 years of age and affe...

Ketoconazole (KCZ), an imidazole anti-fungal agent, is known to be effective for the treatment of seborrheic dermatitis and dandruff. In addition, 2% KCZ shampoo was found to improve hair density and the size and proportion of anagen follicles in androgenetic alopecia (AGA) [1] and, in combination with finasteride, to have an additive effect for AGA [2]. Recently, it has been reported that topi...

Cellular hair growth therapy is an emerging approach to alopecia. Recently, Tsuboi et al. (J Am Acad Dermatol. 2020;83,109–116.) have observed hair-growth stimulation by dermal-sheath-cup cells in patients with androgenic Hair follicle-associated pluripotent (HAP) stem cells, originate the bulge area and express nestin, been shown differentiate multiple cell types including keratinocytes, neuro...

In androgenic alopecia (AGA), hair follicles in the balding scalp miniaturize. This is accompanied by shortened anagen, premature catagen and longer telogen. There are no changes to bulge cells (BC) AGA but there a decrease progenitor cells. We hypothesize loss of progenitors due aberrant signaling from dermal papilla (DP) scalp, which important for BC activation anagen induction. could increas...